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  1. No Access

    Article

    Tight junction proteins at the blood–brain barrier: far more than claudin-5

    At the blood–brain barrier (BBB), claudin (Cldn)-5 is thought to be the dominant tight junction (TJ) protein, with minor contributions from Cldn3 and -12, and occludin. However, the BBB appears ultrastructural...

    Philipp Berndt, Lars Winkler, Jimmi Cording… in Cellular and Molecular Life Sciences (2019)

  2. Article

    Open Access

    CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity

    Casein kinase 2 (CK2) is a ubiquitously expressed Ser/Thr kinase with multiple functions in the regulation of cell proliferation and transformation. In targeting adherens and tight junctions (TJs), CK2 modulat...

    Max J Dörfel, Julie K Westphal, Christian Bellmann… in Cell Communication and Signaling (2013)

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  3. No Access

    Article

    Elucidating the principles of the molecular organization of heteropolymeric tight junction strands

    Paracellular barrier properties of tissues are mainly determined by the composition of claudin heteropolymers. To analyze the molecular organization of tight junctions (TJ), we investigated the ability of clau...

    Jörg Piontek, Susanne Fritzsche, Jimmi Cording… in Cellular and Molecular Life Sciences (2011)

  4. No Access

    Article

    Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules

    Tight junctions control paracellular permeability. Here, we analyzed the impact of residues in the second extracellular loop (ECL2) of mouse claudin-5 on paracellular permeability. Stable expression of claudin-5w...

    Christian Piehl, Jörg Piontek, Jimmi Cording… in Cellular and Molecular Life Sciences (2010)