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Article
Nonlinear Disturbance Observer Incorporated Model Predictive Strategy for Wheeled Mobile Robot’s Trajectory Tracking Control
In this paper, we discuss a nonlinear disturbance observer-based double closed-loop control system for managing a wheeled mobile robot (WMR) and achieving trajectory tracking control. The focus of our study is...
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Article
Open AccessCharacterizing sensitivity and coverage of clinical WGS as a diagnostic test for genetic disorders
Due to its reduced cost and incomparable advantages, WGS is likely to lead to changes in clinical diagnosis of rare and undiagnosed diseases. However, the sensitivity and breadth of coverage of clinical WGS as...
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Article
Open AccessMolecular diagnosis of non-syndromic hearing loss patients using a stepwise approach
Hearing loss is one of the most common birth disorders in humans, with an estimated prevalence of 1–3 in every 1000 newborns. This study investigates the molecular etiology of a hearing loss cohort using a ste...
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Article
Concurrent hearing and genetic screening in a general newborn population
Newborn hearing screening is not designed to detect delayed-onset prelingual hearing loss or aminoglycoside-antibiotic-induced ototoxicity. Cases with severe to profound hearing loss have been reported to have...
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Article
Open AccessIncreased diagnostic yield by reanalysis of data from a hearing loss gene panel
Congenital hearing loss affects approximately 1–2 infants out of every 1000, with 50% of the cases resulting from genetic factors. Targeted gene panels have been widely used for genetic diagnosis of hearing lo...
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Article
Open AccessEvolutionarily significant A-to-I RNA editing events originated through G-to-A mutations in primates
Recent studies have revealed thousands of A-to-I RNA editing events in primates, but the origination and general functions of these events are not well addressed.
