8 Result(s)
within
Jieun Park
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessImplication of high variance in germplasm characteristics
The beauty of conserving germplasm is the securement of genetic resources with numerous important traits, which could be utilized whenever they need to be incorporated into current cultivars. However, it would...
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Article
Open AccessAuthor Correction: Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the develo** mouse brain and human neurons
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Article
Open AccessTanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the develo** mouse brain and human neurons
mTOR signaling, involving mTORC1 and mTORC2 complexes, critically regulates neural development and is implicated in various brain disorders. However, we do not fully understand all of the upstream signaling co...
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Article
Open AccessATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress
Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability under replication stress. Here, we report that ATAD5,...
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Article
Open AccessRegulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes
Replication-Factor-C (RFC) and RFC-like complexes (RLCs) mediate chromatin engagement of the proliferating cell nuclear antigen (PCNA). It remains controversial how RFC and RLCs cooperate to regulate PCNA load...
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Article
Open AccessA Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer
The epidermal growth factor receptor (EGFR) inhibitors such as erlotinib and gefitinib are widely used for treatment of non-small cell lung cancer (NSCLC), but they have shown limited efficacy in an unselected...
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Article
Open AccessGlobal gene expression profiling for fruit organs and pathogen infections in the pepper, Capsicum annuum L.
Hot pepper (Capsicum annuum) is one of the most consumed vegetable crops in the world and useful to human as it has many nutritional and medicinal values. Genomic resources of pepper are publically available sinc...
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Article
Open AccessNeuroprotective effect of Ruminococcus albus on oxidatively stressed SH-SY5Y cells and animals
Recent evidence shows that the gut microbiota has an important role in gut-brain crosstalk and is linked to neuronal disorders. The aim of this study was to investigate the effects of intestinal Ruminococcus albu...
