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Hypoglycemic mechanism of polysaccharide from Cyclocarya paliurus leaves in type 2 diabetic rats by gut microbiota and host metabolism alteration

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    Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a

    Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. ...

    Yonggan Sun, Qixing Nie, Shanshan Zhang, Huijun He, Sheng Zuo in Nature Communications (2023)