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Article
Open AccessOil-soluble polymer brushes-functionalized nanoMOFs for highly efficient friction and wear reduction
Nanomaterials as lubricating oil additives have attracted significant attention because of their designable composition and structure, suitable mechanical property, and tunable surface functionalities. However...
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Article
Open AccessExploring the oncogenic potential of circSOD2 in clear cell renal cell carcinoma: a novel positive feedback loop
Existing studies have found that circular RNAs (circRNAs) act as sponges for micro RNAs (miRNAs) to control downstream genes. However, the specific functionalities and mechanisms of circRNAs in human clear cel...
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Open AccessGlucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival
Low glucose is a common microenvironment for rapidly growing solid tumors, which has developed multiple approaches to survive under glucose deprivation. However, the specific regulatory mechanism remains large...
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Article
The effects of brightness and prominent colors on outdoor thermal perception in Chongqing, China
Outdoor thermal comfort has become an important factor affecting human mental and physical health due to rapid urbanization. This study aimed to investigate the influence of brightness and prominent colors on ...
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Article
Open AccessExploring better image captioning with grid features
Nowadays, Artificial Intelligence Generated Content (AIGC) has shown promising prospects in both computer vision and natural language processing communities. Meanwhile, as an essential aspect of AIGC, image to...
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Article
Open AccessSpatio-temporal expression patterns of glycine-rich beta proteins and cysteine-rich beta proteins in setae development of Gekko japonicus
Setae on the pad lamellae of the Japanese gecko Gekko japonicus (Schlegel, 1836), a vital epidermal derivative, are primarily composed of cornified beta-proteins (CBPs) and play a pivotal role in adhesion and cli...
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Article
Open AccessStructural domain in the Titin N2B-us region binds to FHL2 in a force-activation dependent manner
Titin N2B unique sequence (N2B-us) is a 572 amino acid sequence that acts as an elastic spring to regulate muscle passive elasticity. It is thought to lack stable tertiary structures and is a force-bearing reg...
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Article
Complete hydrogenolysis of mixed plastic wastes
The accumulation of plastic waste in the environment has led to a global crisis with severe consequences for wildlife and ecosystems. Upcycling offers a promising solution for reducing plastic waste by convert...
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Article
Open AccessFlash healing of laser-induced graphene
The advancement of laser-induced graphene (LIG) technology has streamlined the fabrications of flexible graphene devices. However, the ultrafast kinetics triggered by laser irradiation generates intrinsic amor...
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Exploring Cutting-Edge Approaches to Potentiate Mesenchymal Stem Cell and Exosome Therapy for Myocardial Infarction
Cardiovascular diseases (CVDs) continue to be a significant global health concern. Many studies have reported promising outcomes from using MSCs and their secreted exosomes in managing various cardiovascular-r...
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Article
A lightweight multi-granularity asymmetric motion mode video frame prediction algorithm
Due to the increasing demand for improved accuracy in video prediction tasks, there has been a noticeable trend in deepening network layers and adopting more intricate architectures. Although these approaches ...
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Open AccessThe m6A reader IGF2BP2 regulates glycolytic metabolism and mediates histone lactylation to enhance hepatic stellate cell activation and liver fibrosis
Evidence for the involvement of N6-Methyladenosine (m6A) modification in the etiology and progression of liver fibrosis has emerged and holds promise as a therapeutic target. Insulin-like growth factor 2 (IGF2) m...
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Preparation of soybean protein isolate-quercetin particles and its application in curcumin-camellia oil Pickering emulsion
In order to improve the stability and bioavailability of camellia oil, as well as expanding its application in aqueous, a complex (SPIQU) was prepared using soybean protein isolate (SPI) and quercetin (Qu) as ...
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Open AccessStudy on blasting fragmentation mechanism of burnt rock in open-pit coal mine
A large number of burnt rocks in some open-pit mines in **njiang, Inner Mongolia and Ningxia have a great influence on the blasting effect. For this kind of rock, through the analysis of physical and chemical ...
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Open AccessFerroptotic alveolar epithelial type II cells drive TH2 and TH17 mixed asthma triggered by birch pollen allergen Bet v 1
Asthma is a common allergic disease characterized by airway hypersensitivity and airway remodeling. Ferroptosis is a regulated death marked by iron accumulation and lipid peroxidation. Several environmental po...
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Open AccessExploring TRF2-Dependent DNA Distortion Through Single-DNA Manipulation Studies
TRF2 is a component of shelterin, a telomere-specific protein complex that protects the ends of mammalian chromosomes from DNA damage signaling and improper repair. TRF2 functions as a homodimer and its intera...
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Open AccessT-type voltage-gated channels, Na+/Ca2+-exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration
Inherited retinal degenerations (IRDs) are a group of untreatable and commonly blinding diseases characterized by progressive photoreceptor loss. IRD pathology has been linked to an excessive activation of cyc...
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Article
Synthesis and fluorescence mechanism investigation on two novel benzidine AIE compounds
Two novel fluorescent compounds TTPA and TBPH were synthesized by Suzuki coupling reaction. The fluorescence intensity of TTPA and TBPH increased with the increasing of aggregation degree. Fluorescence test an...
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Article
Processing of titanium alloys with improved efficiency and accuracy by laser and electrochemical machining
The fabrication of microstructures with high efficiency and accuracy on titanium alloys presents significant challenges due to stringent quality requirements. Hybrid laser and electrochemical machining (LECM) ...
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Article
Open AccessMolecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy
Procaspase 9 is the initiator caspase for apoptosis, but how its levels and activities are maintained remains unclear. The gigantic Inhibitor-of-Apoptosis Protein BIRC6/BRUCE/Apollon inhibits both apoptosis an...
