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Article
Open AccessSSGAN: A Semantic Similarity-Based GAN for Small-Sample Image Augmentation
Image sample augmentation refers to strategies for increasing sample size by modifying current data or synthesizing new data based on existing data. This technique is of vital significance in enhancing the per...
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Article
Open AccessE-cadherin maintains the undifferentiated state of mouse spermatogonial progenitor cells via β-catenin
Cadherins play a pivotal role in facilitating intercellular interactions between spermatogonial progenitor cells (SPCs) and their surrounding microenvironment. Specifically, E-cadherin serves as a cellular mar...
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Article
Open AccessThe upregulation of stromal antigen 3 expression suppresses the phenotypic hallmarks of hepatocellular carcinoma through the Smad3-CDK4/CDK6-cyclin D1 and CXCR4/RhoA pathways
The stromal antigen 3 (STAG3) gene encodes an adhesion complex subunit that can regulate sister chromatid cohesion during cell division. Chromosome instability caused by STAG3 gene mutation may potentially pro...
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Article
Open AccessAberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes
Androgen/androgen receptor (AR) signaling pathways are essential for prostate tumorigenesis. However, the fundamental mechanisms underlying the AR functioning as a tumor promoter in inducing prostatic oncogene...
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Article
Open AccessANKFN1 plays both protumorigenic and metastatic roles in hepatocellular carcinoma
Ankyrin repeat and fibronectin type III domain containing 1 (ANKFN1) is reported to be involved in human height and developmental abnormalities, but the expression profile and molecular function of ANKFN1 in h...
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Chapter and Conference Paper
How to Evaluate a Good Conversation? An Evaluation Framework for Chat Experience in Smart Home
With the development of artificial intelligence technology, more and more smart devices equipped with smart conversational agents, which can engage in chat or free conversation with human. However, the human-m...
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Article
An optimization model of light intensity and nitrogen concentration coupled with yield and quality
The nitrogen content of nutrient solution and light intensity are two crucial factors affecting the yield and quality of controlled environment hydroponic vegetables. In this study, Purple Bok Choy (Brassica rapa
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Article
Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis
Polyglutamine (polyQ) tract polymorphism within the human androgen receptor (AR) shows population heterogeneity. African American men possess short polyQ tracts significantly more frequently than Caucasian Ame...
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Chapter and Conference Paper
Evaluating Response Delay of Multimodal Interface in Smart Device
Multimodal interface based on natural language processing (NLP) technology is becoming more and more popular. Many studies show that response delay is a key factor to evaluate multimodal interface performance ...
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Chapter
Chemoprevention and Angiogenesis
An estimated one in five Americans will develop skin cancer in their lifetime. In 2016, melanoma is estimated to account for approximately 5% (76380) of all expected new cancer cases by the American cancer soc...
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Article
Quantitative determination of 2-amino-2-(2-(4′-(2-propyloxazol-4-yl)-[1,1′-biphenyl]-4-yl)ethyl)propane-1,3-diol and its active phosphorylated metabolite in rat blood by LC–MS/MS and application to PK/PD analysis
A sensitive and specific LC–MS/MS method was developed and validated for simultaneous determination of 2-amino-2-(2-(4′-(2-propyloxazol-4-yl)-[1,1′-biphenyl]-4-yl)ethyl)propane-1,3-diol (SYL930) and its active...
