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Article
Exploring potential SARS-CoV-2 Mpro non-covalent inhibitors through docking, pharmacophore profile matching, molecular dynamic simulation, and MM-GBSA
In the replication of SARS-CoV-2, the main protease (Mpro/3CLpro) is significant. It is conserved in a number of novel coronavirus variations, and no known human proteases share its cleavage sites. Therefore, ...
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Article
Open AccessThe polymorphism analysis and epitope predicted of Alphapapillomavirus 9 E6 in Sichuan, China
The Alphapapillomavirus 9 (α-9 HPV) is a member of the Alphapapillomavirus genus and Papillomaviridae family. These viruses are almost all carcinogenic HPV, which is closely related to 75% of invasive cervical...
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Article
Open AccessThe genetic variability, phylogeny and functional significance of E6, E7 and LCR in human papillomavirus type 52 isolates in Sichuan, China
Variations in human papillomavirus (HPV) E6 and E7 have been shown to be closely related to the persistence of the virus and the occurrence and development of cervical cancer. Long control region (LCR) of HPV ...
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Article
Open AccessGenetic variability of human papillomavirus type 39 based on E6, E7 and L1 genes in Southwest China
Human papillomavirus type 39 associated with genital intraepithelial neoplasia and invasive cancers, has a high prevalence in Southwest China. HPV E6, E7 are two main papillomavirus oncoproteins, closely relat...
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Article
Open AccessIdentification of variants and therapeutic epitopes in HPV-33/HPV-58 E6 and E7 in Southwest China
Human papillomavirus (HPV) E6 and E7 oncoproteins play a crucial role in HPV-related diseases, such as cervical cancer, and can be used as ideal targets for therapeutic vaccines. Human leukocyte antigen (HLA) ...
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Chapter and Conference Paper
Global Motion Pattern Based Event Recognition in Multi-person Videos
Event analysis in multi-person videos is a great challengeable task, especially in the sports videos due to the intensive and fast movement of players with serious occlusions. In this paper, we propose a globa...
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Chapter and Conference Paper
An Effective Face Verification Algorithm to Fuse Complete Features in Convolutional Neural Network
Face verification for on line application is a difficult problem and many researchers have tried to solve it by convolutional neural network. Among of them, most works used the last-hidden layer as the feature...
