114 Result(s)
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Article
Open AccessmiR-548ag promotes DPP4 expression in hepatocytes through activation of TLR(7/8)/NF-κB pathway
In our previous study, we identified a notable increase in miR-548ag content after obesity, which contributes to the progression of Type 2 diabetes Mellitus(T2DM) through the up-regulation of Dipeptidyl Peptid...
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Open AccessImproved efficacy and safety of zanubrutinib versus ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL) in China: a subgroup of ALPINE
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has different epidemiology in Chinese vs. Western patients, but there are few studies of CLL/SLL in large populations of Chinese patients. ALPI...
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Open AccessRisk factors, impact and treatment of postoperative lymphatic leakage in children with abdominal neuroblastoma operated on by laparotomy
Lymphatic leakage is one of the postoperative complications of neuroblastoma. The purpose of this study is to summarize the clinical characteristics and risk factors of lymphatic leakage and try to find effect...
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Open AccessMitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway
The mitotic MTH1 inhibitor TH1579 is a dual inhibitor that inhibits mitosis and incorporation of oxidative DNA damage and leads to cancer-specific cell death. The response to immune checkpoint inhibitor (ICI) ...
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Article
BDIS-SLAM: a lightweight CPU-based dense stereo SLAM for surgery
Common dense stereo simultaneous localization and map** (SLAM) approaches in minimally invasive surgery (MIS) require high-end parallel computational resources for real-time implementation. Yet, it is not al...
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Open AccessThe relationship between serum resolvin D1, NLRP3, cytokine levels, and adolescents with first-episode medication-naïve major depressive disorder
Inflammation has become a critical pathological mechanism of Major Depressive Disorder (MDD). NLRP3 is a critical inflammatory pathway to maintain the immune balance. Recently, preclinical evidence showed that...
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Open AccessThe influencing factors of hearing protection device usage among noise-exposed workers in Guangdong Province: a structural equation modeling-based survey
There are numerous complex barriers and facilitators to continuously wearing hearing protection devices (HPDs) for noise-exposed workers. Therefore, the present study aimed to investigate the relationship betw...
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Cerebral circulation time on DSA after thrombectomy associated with hemorrhagic transformation in acute ischemic stroke
To investigate the association between cerebral circulation time (CCT) on digital subtraction angiography immediately after thrombectomy and hemorrhagic transformation (HT) in acute ischemic stroke (AIS).
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Article
Open AccessAssociation of non-alcoholic fatty liver disease with self-reported osteoarthritis among the US adults
The association between non-alcoholic fatty liver disease (NAFLD) and osteoarthritis (OA) has not been well elucidated. The aim of the present study was to investigate the association between NAFLD and OA in t...
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Article
Open AccessTough gel adhesive is an effective method for meniscal repair in a bovine cadaveric study
To test tough gel adhesives to repair meniscus tears under relevant loading conditions and determine if they have adequate biomechanical properties to repair meniscus tears in a bovine cadaveric study.
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Open AccessIs remnant preservation in anterior cruciate ligament reconstruction superior to the standard technique? An overview of systematic reviews
Anterior cruciate ligament injury is a common knee joint injury. Anterior cruciate ligament reconstruction is a common surgical treatment to treat anterior cruciate ligament injury. It may have certain advanta...
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Open AccessDiagnosis of leptospira by metagenomics next-generation sequencing with extracorporeal membrane oxygenation support: a case report
Leptospirosis is an infectious disease caused by pathogenic Leptospira spp., which could result in severe illnesses. Indirect contact with these pathogens is more common. Individuals could contract this disease t...
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Open AccessPediatric adrenocortical carcinoma: clinical features and application of neoadjuvant chemotherapy
To summarize the clinical characteristics of children with adrenocortical carcinoma (ACC) and preliminarily explore the indications for and efficacy of neoadjuvant chemotherapy in certain patients.
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Open AccessImpacts of exposure to humidex on cardiovascular mortality: a multi-city study in Southwest China
Many studies have reported the association between ambient temperature and mortality from cardiovascular disease (CVD). However, the health effects of humidity are still unclear, much less the combined effects...
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Open AccessHepatitis B reactivation in cancer patients receiving immune checkpoint inhibitors: a systematic review and meta-analysis
Immunotherapy shows promise as a treatment option for various cancers. However, there is growing concern over potential complications from hepatitis B virus (HBV) reactivation after checkpoint blockade immunot...
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Dual-layer detector spectral CT for predicting p16 status in head and neck squamous cell carcinoma
HPV-positive head and neck squamous cell carcinoma (HNSCC) differs from HPV-negative HNSCC in clinical features, biological behavior, pathological manifestations, cytogenetics and tend to have better outcome. ...
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Open AccessNoninvasive Imaging OX40+ Activated T Cells Provides Early Warning of Rheumatoid Arthritis
The goal of this study was to develop an imaging probe—IRDye-680RD-OX40 mAb—that can be used for noninvasive imaging and optical imaging of rheumatoid arthritis (RA). OX40/OX40 ligand (OX40L) interactions have...
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Open AccessEfficacy and safety of **an-Lian-Jie-Du optimization decoction as an adjuvant treatment for prevention of recurrence in patients with stage IIIB/IIIC colon cancer: study protocol for a multicentre, randomized controlled trial
Colon cancer remains one of the most prevalent cancers worldwide. Unfortunately, there are no recognized and effective therapeutic strategies to prevent tumor recurrence after radical resection and chemotherap...
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Expression and prognostic signatures of m6A-related lncRNAs in hepatocellular carcinoma
N6-methyladenosine (m6A) is a common modification and plays an important role in various biological processes, but m6A-related lncRNA functions in hepatocellular carcinoma (HCC) have not been systematically cl...
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Open AccessPrognostic impact of in-hospital hemoglobin decline in non-overt bleeding ICU patients with acute myocardial infarction
The prognostic value of in-hospital hemoglobin drop in non-overt bleeding patients with acute myocardial infarction (AMI) admitted to the intensive care unit (ICU) remains insufficiently investigated.
