128 Result(s)
within
Jianyu **
Life Sciences
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Article
Open AccessWhole-genome analysis reveals distinct adaptation signatures to diverse environments in Chinese domestic pigs
Long-term natural and artificial selection has resulted in many genetic footprints within the genomes of pig breeds across distinct agroecological zones. Nevertheless, the mechanisms by which these signatures ...
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Open AccessEffects of the pleiotropic regulator DasR on lincomycin production in Streptomyces lincolnensis
The lincoamide antibiotic lincomycin, derived from Streptomyces lincolnensis, is widely used for the treatment of infections caused by gram-positive bacteria. As a common global regulatory factor of GntR family, ...
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Functional Characterization of Chinese Cabbage BrCML49 Gene in Pollen Germination and Pollen Tube Elongation and the Regulation of Ca2+-Mediated Self-Incompatibility Response
Self-incompatibility (SI) is a genetic mechanism that promotes out-breeding and maintains genetic diversity in plant species. The inhibition of pollen germination and pollen tube growth is one of the major cha...
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Open AccessInsights into the role of adipose-derived stem cells and secretome: potential biology and clinical applications in hypertrophic scarring
Scar tissue is the inevitable result of repairing human skin after it has been subjected to external destructive stimuli. It leads to localized damage to the appearance of the skin, accompanied by symptoms suc...
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Dynamic intrauterine crosstalk promotes porcine embryo implantation during early pregnancy
Dynamic crosstalk between the embryo and mother is crucial during implantation. Here, we comprehensively profile the single-cell transcriptome of pig peri-implantation embryos and corresponding maternal endome...
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A novel SOX10 mutation causing Waardenburg syndrome type 2 by expressing a truncated and dysfunctional protein in a Chinese child
This study aimed to identify the causative variants in a patient with Waardenburg syndrome (WS) type 2 using whole exome sequencing (WES).
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Terrihabitans rhizophilus sp. nov., isolated from the rhizosphere soil of plant in temperate semi-arid steppe
A bacterial strain PJ23T was isolated from the rhizosphere soil of Elymus dahuricus Turcz. sampled from a temperate semi-arid steppe in the northern of Inner Mongolia Autonomous Region, China. The strain is Gram-...
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Long non-coding RNA CCAT1 acts as an oncogene to promote radiation resistance in lung adenocarcinoma: an epigenomics-based investigation
Long non-coding RNAs (lncRNAs) appear to be the crucial modulators in various processes and critically influence the oncogenesis. As one of the LncRNAs, LncRNA CCAT1 has been reported to be closely associated ...
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Fertilization Methods Effect Spring Wheat Yield and Soil CH4 Fluxes in the Loess Plateau of China
Dryland agricultural soils are recognized as significant sites of methane (CH4) absorption, making them integral to the global CH4 budget. Nitrogen fertilization is commonly used by growers in these regions to ob...
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Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway
In hyperlipidemia-induced osteoporosis, bone marrow mesenchymal stem cells (BMSCs) differentiate into more adipocytes than osteoblasts, leading to decreased bone formation. It is vital to elucidate the effects...
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Open AccessDoes arbuscular mycorrhizal fungi inoculation influence soil carbon sequestration?
Whether arbuscular mycorrhizal fungi (AMF) inoculation promotes soil C sequestration is largely unknown. Here, meta-analysis and logistic regression were applied to study the ecological effects of AMF inoculat...
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Effects of temperature on fertilization, hatching, larval growth, ingestion, metabolism, and metamorphosis of the purple sea urchins, Heliocidaris crassispina
It is crucial to understand the role of temperature in rearing sea urchin larvae for large-scale production of sea urchin seeds. The development of purple sea urchins, Heliocidaris crassispina, such as fertilizat...
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Fungal communities are more sensitive to mildew than bacterial communities during tobacco storage processes
Mildew poses a significant threat to tobacco production; however, there is limited information on the structure of the abundant and rare microbial subcommunities in moldy tobacco leaves. In this study, we empl...
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Cytotoxic activity of cordycepin produced by marine-derived fungus Emericella sp. against HT29 human colon cancer cell lines
Colorectal cancer accounted for the third most common cancer in the world. The search for new drug candidates that can be used for colorectal cancer treatment from marine-derived fungi, Emericella sp. The present...
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Open AccessExosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of lung adenocarcinoma through mircroRNA-15a-5p/31-5p
Exosomes are a new class of molecular entities in the metastatic microenvironment, which can mediate bidirectional communication between cells. While exosomes-mediated interactions between tumor cells and othe...
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Open AccessEffect of Purpureocillium lilacinum on inter-root soil microbial community and metabolism of tobacco
Numerous chemical pesticides have been used in agricultural production to combat crop diseases and pests. Despite ensuring certain economic advantages, they have also resulted in issues like environmental cont...
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Open AccessHistone acetylation by HBO1 (KAT7) activates Wnt/β-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia
B-cell acute lymphoblastic leukemia (B-ALL) is an aggressive hematological disorder with a dismal prognosis. The dysregulation of histone acetylation is of great significance in the pathogenesis and progressio...
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JAM-A Overexpression in Human Umbilical Cord-Derived Mesenchymal Stem Cells Accelerated the Angiogenesis of Diabetic Wound By Enhancing Both Paracrine Function and Survival of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) is promising in promoting wound healing mainly due to their paracrine function. Nonetheless, the transplanted MSCs presented poor survival with cell dysfunction and paracrine prob...
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Open AccessVmPacC-mediated pH regulation of Valsa mali confers to host acidification identified by comparative proteomics analysis
Apple valsa canker caused by the Ascomycete fungus Valsa mali is one of the most serious diseases of apple, resulting in huge economic losses in the apple-growing area of China. Previous study found that the path...
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Open AccessEffect of prescribed burning on the small-scale spatial heterogeneity of soil microbial biomass in Pinus koraiensis and Quercus mongolica forests of China
Prescribed burning can alter soil microbial activity and spatially redistribute soil nutrient elements. However, no systematic, in-depth studies have investigated the impact of prescribed burning on the spatia...
