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Article
Open AccessSustained growth of sulfur hexafluoride emissions in China inferred from atmospheric observations
Sulfur hexafluoride (SF6) is a potent greenhouse gas. Here we use long-term atmospheric observations to determine SF6 emissions from China between 2011 and 2021, which are used to evaluate the Chinese national SF
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Article
Open AccessProjected increases in emissions of high global warming potential fluorinated gases in China
China is the largest greenhouse gas emitter in the world and has committed to mitigating global warming through achieving carbon neutrality by 2060. However, detailed information on China’s historical and proj...
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Article
Open AccessInsight of chemical environmental risk and its management from the vinyl chloride accident
The combustion of vinyl chloride (VC) after the train derailment accident in Ohio, USA in February, 2023 has caused widespread concern around the world. This paper tried to analyze several issues concerning th...
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Article
Open AccessLong-term outcomes of left bundle branch area pacing versus biventricular pacing in patients with heart failure and complete left bundle branch block
Left bundle branch area pacing (LBBAP) has developed in an effort to improve cardiac resynchronization therapy (CRT). We aimed to compare the long-term clinical outcomes between LBBAP and biventricular pacing ...
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Article
Open AccessRapid increase in dichloromethane emissions from China inferred through atmospheric observations
With the successful implementation of the Montreal Protocol on Substances that Deplete the Ozone Layer, the atmospheric abundance of ozone-depleting substances continues to decrease slowly and the Antarctic oz...
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Article
Thermal decomposition and kinetics of electrically controlled solid propellant through thermogravimetric analysis
The thermal decomposition behavior of electrically controlled solid propellant (ECSP) with hydroxyl ammonium nitrate as oxidizer and polyvinyl alcohol as binder was investigated through thermogravimetric analy...
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Article
Thermodynamic properties of polyvinyl alcohol binder of electrically controlled solid propellant
The thermodynamic properties of polyvinyl alcohol (PVA) binder of electrically controlled solid propellant with different degrees of polymerization and alcoholysis were studied via multiple thermochemical meth...
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Article
Open AccessGenomic analysis of transcriptional networks directing progression of cell states during MGE development
Homeodomain (HD) transcription factor (TF) NKX2–1 critical for the regional specification of the medial ganglionic eminence (MGE) as well as promoting the GABAergic and cholinergic neuron fates via the inducti...
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Article
Modulation of tissue repair by regeneration enhancer elements
How tissue regeneration programs are triggered by injury has received limited research attention. Here we investigate the existence of enhancer regulatory elements that are activated in regenerating tissue. Tr...
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Article
Open AccessThe effects of lung and prostate cancer bone metastasis on serum osteoprotegerin levels: a meta-analysis
Bone metastasis leads to skeletal-related events in final-stage cancer patients. The incidence of prostate and lung cancers increases yearly; these cancers readily invade the bone. Some recent studies have fou...
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Article
Open AccessMyocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice
Skeletal muscle is the most abundant tissue in the body and is a major source of total energy expenditure in mammals. Skeletal muscle consists of fast and slow fiber types, which differ in their energy usage, ...
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Virus-Mediated Expression of DREADDs for In Vivo Metabolic Studies
During the past few years, CNO-sensitive designer G protein-coupled receptors (GPCRs) known as DREADDs (designer receptors exclusively activated by designer drugs) have emerged as powerful new tools for the study...
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Article
Estimated HCFC-142b emissions in China: 2000–2050
1-Chloro-1,1-difluoroethane (HCFC-142b) was both ozone depleting substance under restriction of the Montreal Protocol on Substances that Deplete the Ozone Layer (Montreal Protocol) and potent gree...
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Article
Novel Insights into M3 Muscarinic Acetylcholine Receptor Physiology and Structure
Recent studies with M3 muscarinic acetylcholine receptor (M3R) mutant mice suggest that drugs selectively targeting this receptor subtype may prove useful for the treatment of various pathophysiological condition...
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Article
Activation and allosteric modulation of a muscarinic acetylcholine receptor
Despite recent advances in crystallography and the availability of G-protein-coupled receptor (GPCR) structures, little is known about the mechanism of their activation process, as only the β2 adrenergic receptor...
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Article
Gridded usage inventories of chlordane in China
Chlordane (1,2,4,5,6,7,8,8-octachloro-3a,4,7, 7a-tetra-hydro-4,7-methanoindane) is one of organochlorine pesticides (OCPs) which has been listed as one of the persistent organic pollutants (POPs) to be reduced...
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Article
Experimental study on the ignition and combustion characteristics of a magnesium particle in water vapor
Magnesium is of interest for underwater propulsion due to the superior ignition behavior of magnesium particles and the highly exothermic Mg-water reaction. In this work, the ignition and combustion characteri...
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Article
Open AccessDetermination of dioxin-like polychlorinated biphenyls in soil and moss from Fildes Peninsula, Antarctica
Dioxin-like polychlorinated biphenyls (PCBs) are a class of toxic and persistent chemicals that are often found in the environment. The determination of dioxin-like PCBs in Fildes Peninsula, Antarctica, is rep...
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Article
Structure and dynamics of the M3 muscarinic acetylcholine receptor
The X-ray crystal structure of the M3 muscarinic acetylcholine receptor bound to the bronchodilator drug tiotropium is reported; comparison of this structure with that of the M2 muscarinic acetylcholine recept...
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Article
Endosulfan in the Chinese environment: monitoring and modeling
This paper reviews the usage and emissions of endosulfan, the newest member of the persistent organic pollutants (POPs), in China, and its fate and behavior in Chinese environment. Endosulfan usage in China ha...
