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    Article

    Heat shock factor 1 is a transcription factor of Fas gene

    In mammalian cells, stress-induced expression of heat shock protein is controlled by heat shock factor 1 (HSF1). However, HSF1 functions as a regulator of additional genes. In this study, we observed that heat...

    E. Shunmei, Yuanbo Zhao, Yunhong Huang, Kun Lai, Cha Chen… in Molecules and Cells (2010)

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    Article

    Induction of macroautophagy by heat

    Macroautophagy is a regulated bulk degradation process of cellular components, mainly long-lived proteins or cytoplasmic organelles. Nutrient depletion is a classic inducer of macroautophagy. In this report, w...

    Yuanbo Zhao, Soufang Gong, E. Shunmei, Jiangying Zou in Molecular Biology Reports (2009)

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    Article

    Delivery of HSF1(+) protein using HIV-1 TAT protein transduction domain

    HSF1 is the major transcription factor of HSPs (heat shock proteins) in response to various stresses. Wild type HSF1 (heat shock transcriptional factor 1) is normally inactive, while a constitutively active fo...

    Yonghui Hou, Jiangying Zou in Molecular Biology Reports (2009)

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    Article

    Prevention of chemotherapy-induced alopecia in rodent models

    Alopecia (hair loss) is experienced by thousands of cancer patients every year. Substantial-to-severe alopecia is induced by anthracyclines (e.g., adriamycin), taxanes (e.g., taxol), alkylating compounds (e.g....

    Joaquin J. Jimenez, Stephen M. Roberts, Jessica Mejia… in Cell Stress and Chaperones (2008)