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  1. Article

    Correction: Empaglifozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress

    Ronghua Fang, Jie Chen, Jiangchuan Long, Binghan Zhang, Qixuan Huang in Biogerontology (2024)

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    Article

    Empagliflozin rescues lifespan and liver senescence in naturally aged mice

    Empagliflozin is currently known to decrease blood glucose levels, delay renal failure, and reduce the risk of cardiovascular death and all-cause mortality in patients with type 2 diabetes with cardiovascular ...

    Jiangchuan Long, Ziyu Ren, Yaqian Duan, Wei Tao, ** Li, Shengbing Li, Ke Li in GeroScience (2024)

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    Article

    The SGLT2 inhibitor empagliflozin inhibits skeletal muscle fibrosis in naturally aging male mice through the AMPKα/MMP9/TGF-β1/Smad pathway

    With advancing age, the incidence of sarcopenia increases, eventually leading to a cascade of adverse events. However, there is currently a lack of effective pharmacological treatment for sarcopenia. Sodium-gl...

    Qixuan Huang, Jie Chen, Siqi Liao, Jiangchuan Long, Ronghua Fang in Biogerontology (2024)

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    Article

    Empagliflozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress

    Sodium-glucose cotransporter-2 (SGLT-2) inhibitors have received widespread attention because of their significant protective effects on the kidney. Previous studies have shown that Sirt1, as which is an antia...

    Ronghua Fang, Jie Chen, Jiangchuan Long, Binghan Zhang, Qixuan Huang in Biogerontology (2023)

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    Article

    Effect of GLP-1R rs2254336 and rs3765467 polymorphisms on gastrointestinal adverse reactions in type 2 diabetes patients treated with liraglutide

    Gastrointestinal adverse reactions (GIARs) to liraglutide exhibit significant individual differences in type 2 diabetes. This study investigated the association between glucagon-like peptide-1 receptor (GLP-1R) s...

    Jiangchuan Long, Yongjian Liu, Yaqian Duan in European Journal of Clinical Pharmacology (2022)