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Article
Precise Pentamers with Diverse Monomer Sequences and Their Thermal Properties
Sequenced-defined oligomer has been emerged as one of the hot topics in polymer chemistry due to its capability of precisely controlling both chain length and monomer sequence. Recent efforts have focused on d...
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Article
Open AccessIntra-articular delivery of celastrol by hollow mesoporous silica nanoparticles for pH-sensitive anti-inflammatory therapy against knee osteoarthritis
Celastrol has been proven effective in anti-inflammatory but was limited in the clinic due to the poor solubility and side effects induced by low bioavailability. Osteoarthritis has acidic and inflammatory env...
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Article
The Regulatory Roles of Toll-Like Receptor 4 in Secretions of Type 1/Type 2 Relative Cytokines by Splenocytes and Dendritic Cells Exposed to Clonorchis sinensis Excretory/Secretory Products
The roles of TLR4 in mediation of innate immune response and in regulation of adaptive immune responses triggered by Clonorchis sinensis remain unknown. In the present study, splenocytes derived from C3H/HeN (TLR...
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Article
Gas outburst affected by original rock stress direction
In this paper, it was determined that all of the three-dimensional principal stresses increase with depth and that both the maximum and the minimum stresses tend to be aligned in the horizontal orientation. T...