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Article
Open AccessDynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer
Docetaxel chemotherapy is a standard treatment option for metastatic castrate resistant prostate cancer (mCRPC) patients. To date, the genomic perturbations underlying the emergence of resistance in mCRPC pati...
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Article
Open AccessHigh myosin binding protein H expression predicts poor prognosis in glioma patients
Glioma is the most common and fatal primary brain tumor in humans. Myosin binding protein H (MYBPH), which was first identified as an important myofibrillar constituent of vertebrate skeletal and cardiac muscl...
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Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
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Article
Open AccessTransmission and full-band coherent detection of polarization-multiplexed all-optical Nyquist signals generated by Sinc-shaped Nyquist pulses
All optical method is considered as a promising technique for high symbol rate Nyquist signal generation, which has attracted a lot of research interests for high spectral-efficiency and high-capacity optical ...
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Article
Open AccessHigh Speed All Optical Nyquist Signal Generation and Full-band Coherent Detection
Spectrum efficient data transmission is of key interest for high capacity optical communication systems considering the limited available bandwidth. Transmission of the high speed signal with higher-order modu...
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Article
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
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Article
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
The Cancer Cell Line Encyclopedia presents the first results from a large-scale screen of some 947 cancer cell lines with 24 anticancer drugs, with the aim of identifying specific genomic alterations and gene ...