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  1. Article

    Open Access

    Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer

    Docetaxel chemotherapy is a standard treatment option for metastatic castrate resistant prostate cancer (mCRPC) patients. To date, the genomic perturbations underlying the emergence of resistance in mCRPC pati...

    Winston Tan, Tiantian Zheng, Amy Wang, Joanna Roacho, Seng Thao in Scientific Reports (2022)

  2. Article

    Open Access

    High myosin binding protein H expression predicts poor prognosis in glioma patients

    Glioma is the most common and fatal primary brain tumor in humans. Myosin binding protein H (MYBPH), which was first identified as an important myofibrillar constituent of vertebrate skeletal and cardiac muscl...

    Jianfei Zhang, Qianqiao Guo, Guoxiang Zhang, Xuemei Cao, Wei Chen in Scientific Reports (2022)

  3. No Access

    Article

    Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan in Nature (2019)

  4. Article

    Open Access

    Transmission and full-band coherent detection of polarization-multiplexed all-optical Nyquist signals generated by Sinc-shaped Nyquist pulses

    All optical method is considered as a promising technique for high symbol rate Nyquist signal generation, which has attracted a lot of research interests for high spectral-efficiency and high-capacity optical ...

    Junwen Zhang, Jianjun Yu, Nan Chi in Scientific Reports (2015)

  5. Article

    Open Access

    High Speed All Optical Nyquist Signal Generation and Full-band Coherent Detection

    Spectrum efficient data transmission is of key interest for high capacity optical communication systems considering the limited available bandwidth. Transmission of the high speed signal with higher-order modu...

    Junwen Zhang, Jianjun Yu, Yuan Fang, Nan Chi in Scientific Reports (2014)

  6. Article

    Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan in Nature (2012)

  7. No Access

    Article

    The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    The Cancer Cell Line Encyclopedia presents the first results from a large-scale screen of some 947 cancer cell lines with 24 anticancer drugs, with the aim of identifying specific genomic alterations and gene ...

    Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan in Nature (2012)