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Article
Open AccessExosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammation
The activation of the complement system and subsequent inflammatory responses are important features of myocardial ischemia/reperfusion (I/R) injury. Exosomes are nanoscale extracellular vesicles that play a s...
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Article
A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice
Besides generating vision, light modulates various physiological functions, including mood. While light therapy applied in the daytime is known to have anti-depressive properties, excessive light exposure at n...
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Article
Open AccessModeling the relationship of diverse genomic signatures to gene expression levels with the regulation of long-range enhancer-promoter interactions
Enhancer–promoter (E–P) interaction is an essential component of cis-regulatory regulation for gene expression. However, to comprehensively study the gene expression with the regulation of long-range E–P inter...