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  1. Article

    Open Access

    Exosomal HSP90 induced by remote ischemic preconditioning alleviates myocardial ischemia/reperfusion injury by inhibiting complement activation and inflammation

    The activation of the complement system and subsequent inflammatory responses are important features of myocardial ischemia/reperfusion (I/R) injury. Exosomes are nanoscale extracellular vesicles that play a s...

    **ao-Fang Cheng, Shi-Tao He, Guo-Qiang Zhong, Jian-Jun Meng in BMC Cardiovascular Disorders (2023)

  2. No Access

    Article

    A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice

    Besides generating vision, light modulates various physiological functions, including mood. While light therapy applied in the daytime is known to have anti-depressive properties, excessive light exposure at n...

    Kai An, Huan Zhao, Ying Miao, Qi Xu, Yu-Fei Li, Yu-Qian Ma in Nature Neuroscience (2020)

  3. Article

    Open Access

    Modeling the relationship of diverse genomic signatures to gene expression levels with the regulation of long-range enhancer-promoter interactions

    Enhancer–promoter (E–P) interaction is an essential component of cis-regulatory regulation for gene expression. However, to comprehensively study the gene expression with the regulation of long-range E–P inter...

    Zhen-**ng Feng, Qian-Zhong Li, Jian-Jun Meng in Biophysics Reports (2019)