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Article
Drawing–upsetting–extrusion–clinching of high-strength steel and aluminum alloy
To realize good point connection between high-strength steel and aluminum alloy, a process of drawing–upsetting–extrusion–clinching was proposed. First, the sheets were drawn; then, the bottom of the protrusio...
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Article
The detection of major clades and new species of Mallocybe (Inocybaceae, Agaricales) from China with elongate cheilocystidia
Mallocybe, a member of the ectomycorrhizal mushroom family Inocybaceae, is a newly elevated genus based on Inocybe subg. Mallocybe. Although new species of Mallocybe have continuously been discovered worldwide du...
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Article
Isolation and Screening of High-Yielding α-Amylase Mutants of Bacillus subtilis by Heavy Ion Mutagenesis
To improve fermentative production of α-amylase, heavy-ion mutagenesis technology was used to irradiate Bacillus subtilis (B. subtilis) to obtain the high yielding mutants in this study. After continuous cultivat...
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Article
Phylogenetic analyses, morphological studies, and muscarine detection reveal two new toxic Pseudosperma (Inocybaceae, Agaricales) species from tropical China
As a result of molecular phylogenetic analyses and morphological studies, two new species of the genus Pseudosperma, namely P. fulvidiscum and P. singulare, were discovered in Wuzhishan Nature Reserve of Hainan P...
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Article
Open AccessPhosphoglycerate kinase 1 silencing by a novel microRNA microRNA-4523 protects human osteoblasts from dexamethasone through activation of Nrf2 signaling cascade
Nuclear-factor-E2-related factor 2 (Nrf2) cascade activation can ameliorate dexamethasone (DEX)-induced oxidative injury and death in human osteoblasts. Phosphoglycerate kinase 1 (PGK1) depletion is shown to e...
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Article
Interferon-α2b spray inhalation did not shorten virus shedding time of SARS-CoV-2 in hospitalized patients: a preliminary matched case-control study
Currently, there are no drugs that have been proven to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Because of its broad antiviral activity, interferon (IFN) should be eva...
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Article
Open AccessClinical characteristics of different subtypes and risk factors for the severity of illness in patients with COVID-19 in Zhejiang, China
The outbreak of coronavirus disease 2019 (COVID-19) is now becoming an enormous threat to public health. The clinical spectrum of COVID-19 is extensive, of which critical cases are with rapid disease progressi...
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Article
Open AccessErratum to: Kinetic Characterization of Tyrosinase-catalyzed Oxidation of Four Polyphenols
The article “Kinetic Characterization of Tyrosinase-catalyzed Oxidation of Four Polyphenols”, written by Wan-yu LIU, Congming ZOU, Jian-hua HU, Zi-jun XU, Lu-qin SI, Jun-jun LIU, Jian-geng HUANG, was originall...
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Article
Molecular rotation-caused autocorrelation behaviors of thermal noise in water
The finite autocorrelation time of thermal noise is crucial to unidirectional transportation on the molecular scale. Therefore, it is important to understand the cause of the intrinsic picosecond autocorrelati...
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Article
Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure
A novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, has been rapidly spreading around the world. This study investigates the epidemiologic...
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Article
Open AccessKinetic Characterization of Tyrosinase-catalyzed Oxidation of Four Polyphenols
Phenolic compounds such as chlorogenic acid, cryptochlorogenic acid, neochlorogenic acid and caffeic acid are widely distributed in fruits, vegetables and traditional Chinese medicines with a wide range of bio...
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Article
Scale-up laccase production from Trametes versicolor stimulated by vanillic acid
An efficient strategy for laccase production in Trametes versicolor cultures was developed using vanillic acid as the inducer. The optimized vanillic acid treatment strategy consisted of exposing 2-day-old myceli...
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Article
Development of an efficient process intensification strategy for enhancing Pfu DNA polymerase production in recombinant Escherichia coli
An efficient induction strategy that consisted of multiple additions of small doses of isopropyl-β-D-thiogalactopyranoside (IPTG) in the early cell growth phase was developed for enhancing Pfu DNA polymerase prod...
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Article
Hybrid decompression technique and two-level corpectomy are effective treatments for three-level cervical spondylotic myelopathy
The optimal surgical strategy for multilevel cervical spondylotic myelopathy (CSM) has not been defined, and few comparative researches between hybrid decompression and multilevel corpectomy have been conducte...
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Article
An analysis of reform in administrative system of Chinese higher education
After the founding of the People’s Republic of China, the administrative system of higher education then was characterized as “centralized”, “Tiao and Kuai” were segmented (some higher education institutions w...
