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  1. No Access

    Article

    Preclinical evaluation of 68 Ga-labeled peptide CK2 for PET imaging of NRP-1 expression in vivo

    Neuropilin-1 (NRP-1) is a multifunctional protein involved in a variety of biological processes such as angiogenesis, tumorigenesis and immunomodulation. It was usually overexpressed in many cancer cell lines ...

    Qingzhu Liu, Shuyue Cai, Jiacong Ye… in European Journal of Nuclear Medicine and M… (2024)

  2. No Access

    Article

    EDB-FN targeted probes for the surgical navigation, radionuclide imaging, and therapy of thyroid cancer

    Extradomain B of fibronectin (EDB-FN) is a promising diagnostic and therapeutic biomarker for thyroid cancer (TC). Here, we identified a high-affinity EDB-FN targeted peptide named EDBp (AVRTSAD) and developed...

    Ru** Li, Huihui He, **nling Li… in European Journal of Nuclear Medicine and M… (2023)

  3. Article

    Open Access

    Identification of heptapeptides targeting a lethal bacterial strain in septic mice through an integrative approach

    Effectively killing pathogenic bacteria is key for the treatment of sepsis. Although various anti-infective drugs have been used for the treatment of sepsis, the therapeutic effect is largely limited by the la...

    **aoyan Zhang, Shan Li, Haihua Luo, Shuyue He… in Signal Transduction and Targeted Therapy (2022)

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  4. No Access

    Article

    Sodium Pump Na + /K + ATPase Subunit α1-Targeted Positron Emission Tomography Imaging of Hepatocellular Carcinoma in Mouse Models

    Positron emission tomography (PET) imaging was not efficiently used in the early diagnosis of hepatocellular carcinoma (HCC) due to the lack of appropriate tracers. Sodium pump Na + /K + ATPase subunit α1 (NKA...

    Si Tang, **aoChun Yang, Chao Zhou, Yan Mei, JiaCong Ye… in Molecular Imaging and Biology (2022)