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Article
Open AccessRevolutionizing lymph node metastasis imaging: the role of drug delivery systems and future perspectives
The deployment of imaging examinations has evolved into a robust approach for the diagnosis of lymph node metastasis (LNM). The advancement of technology, coupled with the introduction of innovative imaging dr...
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Article
MSWIFA and cement cooperate in the disposal of soft soil — experimental study on silty sand and silty clay
Municipal solid waste incineration fly ash (MSWIFA) can be reused as a positive additive to strengthen soft soil. In this study, MSWIFA was initially used as a supplementary solidification material in combinat...
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Chapter and Conference Paper
Research on Seismic Response of Single-Tower Cable-Stayed Bridge Across Faults
Near-fault ground motions usually produce irrecoverable permanent ground displacements and trigger various near-fault ground motion effects, which are significantly different from general ground motions and fa...
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Article
Open AccessMetabolomic analysis on the mechanism of nanoselenium alleviating cadmium stress and improving the pepper nutritional value
Selenium (Se) maintains soil-plant homeostasis in the rhizosphere and regulates signaling molecules to mitigate cadmium (Cd) toxicity. However, there has been no systematic investigation of the effects of nano...
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Article
Synthesis and insecticidal activity of novel 1,2,4-triazole derivatives containing trifluoroacetyl moieties
A series of compounds containing trifluoroacetyl groups were synthesized, and their insecticidal activity against Nilaparvata lugens and Aphis craccivora was evaluated. The compound structure was identified by NM...
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Article
Synthesis and fungicidal activity of methyl (E)-1-(2-((E)-2-methoxy-1-(methoxyimino)-2-oxoethyl)benzyl)-2-(1-arylidene)hydrazine-1-carboxylates †‡
To discover novel strobilurin fungicides, a series of methyl (E)-1-(2-((E)-2-methoxy-1-(methoxy-imino)-2-oxoethyl)benzyl)-2-(1-arylidene)hydrazine-1-carboxylates were designed based on the principle of biologi...
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Article
Open AccessIntranasal delivery of replicating mRNA encoding neutralizing antibody against SARS-CoV-2 infection in mice
The lung is the prophylaxis target against SARS-CoV-2 infection, and neutralizing antibodies are a leading class of biological products against various infectious viral pathogen. In this study, we develop a sa...
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Article
Open AccessNanoselenium transformation and inhibition of cadmium accumulation by regulating the lignin biosynthetic pathway and plant hormone signal transduction in pepper plants
Selenium (Se) can promote the growth and resistance of agricultural crops as fertilizers, while the role of nano-selenium (nano-Se) against Cd remains unclear in pepper plants (Capsicum annuum L.). Biofortificati...
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Article
Microwave photonic circulator based on optomechanical-like interactions
The circulator is an important device in quantum information, which can route the input state to a designated output channel. In this work, we propose a scheme to realize a microwave photonic circulator based ...
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Article
Thiosemicarbazones exhibit inhibitory efficacy against New Delhi metallo-β-lactamase-1 (NDM-1)
The superbug infection caused by metallo-β-lactamases (MβLs) carrying drug-resistant bacteria, specifically, New Delhi metallo-β-lactamase (NDM-1) has become an emerging threat. In an effort to develop novel i...
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Article
Open AccessIncreased morbidity of obese mice infected with mouse-adapted SARS-CoV-2
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Article
Surface/Interfacial design and tailoring of polymeric membranes for liquid-phase separation
Synthetic polymer membranes are widely used in many applications, including, among others, water purification, protein separation, and medicine. However, the use of existing polymer membranes faces major chall...
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Article
Open AccessBiallelic SORD pathogenic variants cause Chinese patients with distal hereditary motor neuropathy
Sorbitol dehydrogenase gene (SORD) has been identified as a novel causative gene of recessive forms of hereditary neuropathy, including Charcot–Marie–Tooth disease type 2 and distal hereditary motor neuropathy (d...
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Article
Silencing of DsbA-L gene impairs the PPARγ agonist function of improving insulin resistance in a high-glucose cell model
Disulfide-bond A oxidoreductase-like protein (DsbA-L) is a molecular chaperone involved in the multimerization of adiponectin. Recent studies have found that DsbA-L is related to metabolic diseases including g...
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Article
Open AccessA mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles
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Article
Open AccessEffects of the weight of shoes on calf muscle simulation
The current study investigated the effects of shoes of different weights on calf individual muscle contributions during a running cycle. Twenty male runners ran on a force platform with shoes of four different...
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Article
Open AccessEZH2-inhibitor DZNep enhances apoptosis of renal tubular epithelial cells in presence and absence of cisplatin
The enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and induces the trimethylation of histone H3 lysine 27 (H3K27me3) in the promoter of many key genes; EZH2 acts as a transcriptional repress...
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Article
Bioinformatic prediction of critical genes and pathways involved in longevity in Drosophila melanogaster
The pursuit of longevity has been the goal of humanity since ancient times. Genetic alterations have been demonstrated to affect lifespan. As increasing numbers of pro-longevity genes and anti-longevity genes ...
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Article
1,1-Diaryl compounds as important bioactive module in pesticides
1,1-Diaryl compounds are a series of compounds which possess two aryl groups attached to a central carbon atom. This special structure made it as a very important module in bioactive molecules, and compounds o...
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Article
Open AccessA novel homozygous mutation in the glycerol-3-phosphate dehydrogenase 1 gene in a Chinese patient with transient infantile hypertriglyceridemia: a case report
Transient infantile hypertriglyceridemia (HTGTI) is an autosomal recessive disorder caused by mutations in the glycerol-3-phosphate dehydrogenase 1 (GPD1) gene.
