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Article
Novel insights into the glucose metabolic alterations of freshwater snails: a pathway to molluscicide innovation and snail control strategies
As ecosystem disruptors and intermediate hosts for various parasites, freshwater snails have significant socioeconomic impacts on human health, livestock production, and aquaculture. Although traditional mollu...
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Article
Effect of Sr–Ce modification on the microstructure and mechanical properties of A356 alloy
The effects of Sr–Ce addition on the structure and properties of A356 aluminum alloy are investigated under a constant of Sr content with increasing addition of Ce. When Sr is added to the aluminum melt in com...
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Article
Preparation and improved properties (electrical, mechanical and microwave absorption) of graphene/ZnO/XNBR nanocomposites
A preparation route to fabricate high-performance graphene/rubber elastic nanocomposites was developed by combining the plasma-assisted electrical chemical exfoliation of graphite (PEG) in liquid phase with ca...
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Article
The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma
The small molecule chemical compound cinobufotalin (CB) is reported to be a potential antitumour drug that increases cisplatin (DDP) sensitivity in nasopharyngeal carcinoma. In this study, we first found that ...
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Article
Open AccessElaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation
Finely tuned mitogen-activated protein kinase (MAPK) signaling is important for cancer cell survival. Perturbations that push cells out of the MAPK fitness zone result in cell death. Previously, in a screen of...
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Article
Rare earth-based MOF@mesoporous silica nanoplatform for long-term and luminescence trackable chemotherapy
Develo** the multifunctional nanocarriers for long-term drug release and luminescence traceability is a challenging assignment. In this task, we designed a novel nanoplatform for long-term and luminescence t...
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Article
Open AccessMachine learning based early warning system enables accurate mortality risk prediction for COVID-19
Soaring cases of coronavirus disease (COVID-19) are pummeling the global health system. Overwhelmed health facilities have endeavored to mitigate the pandemic, but mortality of COVID-19 continues to increase. ...
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Article
Anti-oxidative Responses on Hepatic Tissue of Zebrafish (Danio rerio) in a Short Duration of Sub-lethal Concentrations of Cadmium Exposure
The aim of the present study was to identify whether the responses of oxidative stress in zebrafish liver are similar to those in mammalians upon low doses of Cd2+ exposure in short durations. Fish were exposed t...
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Article
Anti-oxidative functions of mt2 and smtB mRNA expression in the gills and brain of zebrafish (Danio rerio) upon cadmium exposure
There were not any past studies about metallothionein isoforms (smtB and mt2) having anti-oxidative functions on zebrafish after Cd2+ exposure. On the other hand, the anti-oxidative enzymatic factors such as supe...