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    Article

    Novel insights into the glucose metabolic alterations of freshwater snails: a pathway to molluscicide innovation and snail control strategies

    As ecosystem disruptors and intermediate hosts for various parasites, freshwater snails have significant socioeconomic impacts on human health, livestock production, and aquaculture. Although traditional mollu...

    Tao Zheng, Jia Hao Liu, Ting Yao Zhu, Bin Li, Jia Shan Li in Parasitology Research (2024)

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    Article

    Effect of Sr–Ce modification on the microstructure and mechanical properties of A356 alloy

    The effects of Sr–Ce addition on the structure and properties of A356 aluminum alloy are investigated under a constant of Sr content with increasing addition of Ce. When Sr is added to the aluminum melt in com...

    **ao-lin Zhang, Jia-hao Liu, Wen-shu Li in International Journal of Metalcasting (2023)

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    Article

    Preparation and improved properties (electrical, mechanical and microwave absorption) of graphene/ZnO/XNBR nanocomposites

    A preparation route to fabricate high-performance graphene/rubber elastic nanocomposites was developed by combining the plasma-assisted electrical chemical exfoliation of graphite (PEG) in liquid phase with ca...

    Che-Kuan Lin, Tse-Ming Huang, Jia-Hao Liu, **g-Wen Tu, Yun-Ting Liu in Polymer Bulletin (2023)

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    Article

    The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc deubiquitination in lung adenocarcinoma

    The small molecule chemical compound cinobufotalin (CB) is reported to be a potential antitumour drug that increases cisplatin (DDP) sensitivity in nasopharyngeal carcinoma. In this study, we first found that ...

    Jia-hao Liu, Hui-ling Yang, Shu-ting Deng, Zhe Hu in Acta Pharmacologica Sinica (2022)

  5. Article

    Open Access

    Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation

    Finely tuned mitogen-activated protein kinase (MAPK) signaling is important for cancer cell survival. Perturbations that push cells out of the MAPK fitness zone result in cell death. Previously, in a screen of...

    Guan-Nan Li, Xue-Jiao Zhao, Zhen Wang in Signal Transduction and Targeted Therapy (2022)

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    Article

    Rare earth-based MOF@mesoporous silica nanoplatform for long-term and luminescence trackable chemotherapy

    Develo** the multifunctional nanocarriers for long-term drug release and luminescence traceability is a challenging assignment. In this task, we designed a novel nanoplatform for long-term and luminescence t...

    Lu-Min Wang, Wen-Yan Liu, Ming-Liang Hu, Jia-Sai Yao, ** Wang, Jia-Hao Liu in Rare Metals (2022)

  7. Article

    Open Access

    Machine learning based early warning system enables accurate mortality risk prediction for COVID-19

    Soaring cases of coronavirus disease (COVID-19) are pummeling the global health system. Overwhelmed health facilities have endeavored to mitigate the pandemic, but mortality of COVID-19 continues to increase. ...

    Yue Gao, Guang-Yao Cai, Wei Fang, Hua-Yi Li, Si-Yuan Wang in Nature Communications (2020)

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    Article

    Anti-oxidative Responses on Hepatic Tissue of Zebrafish (Danio rerio) in a Short Duration of Sub-lethal Concentrations of Cadmium Exposure

    The aim of the present study was to identify whether the responses of oxidative stress in zebrafish liver are similar to those in mammalians upon low doses of Cd2+ exposure in short durations. Fish were exposed t...

    Su Mei Wu, Li-Hsin Shu, Jia-Hao Liu in Bulletin of Environmental Contamination an… (2017)

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    Article

    Anti-oxidative functions of mt2 and smtB mRNA expression in the gills and brain of zebrafish (Danio rerio) upon cadmium exposure

    There were not any past studies about metallothionein isoforms (smtB and mt2) having anti-oxidative functions on zebrafish after Cd2+ exposure. On the other hand, the anti-oxidative enzymatic factors such as supe...

    Su Mei Wu, Li-Hsin Shu, Jia-Hao Liu in Fish Physiology and Biochemistry (2016)