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  1. Article

    Open Access

    Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

    Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

    Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu in Journal of Cancer Research and Clinical On… (2024)

  2. No Access

    Article

    SoccerNet 2023 challenges results

    The SoccerNet 2023 challenges were the third annual video understanding challenges organized by the SoccerNet team. For this third edition, the challenges were composed of seven vision-based tasks split into t...

    Anthony Cioppa, Silvio Giancola, Vladimir Somers, Floriane Magera in Sports Engineering (2024)

  3. No Access

    Article

    Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages

    Liver X receptors (LXRs) which link lipid metabolism and inflammation, were overexpressed in experimental rheumatoid arthritis (RA) rats as observed in our previous studies, while suppression of LXRα by silybi...

    De-chong Zheng, Jia-qin Hu, Chu-tian Mai, Li Huang, Hua Zhou in Acta Pharmacologica Sinica (2024)

  4. No Access

    Article

    In situ revealing C–C coupling behavior for CO2 electroreduction on tensile strain Ptδ+–Cuδ+ dual sites

    Engineering the desired dual metal sites to realize C–C coupling of CO2 is of great importance for the practical applications of CO2 electroreduction reaction (CER). Herein, an efficient strategy for constructing...

    Feng-Ya Ma, Pu Huang, **g Zhou, Hong-Wei Zeng, Jia-Wei Zhang, Hui Zhao in Rare Metals (2024)

  5. Article

    Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence

    Jian-chao Xue, Li Feng, Hui Li, ** Zhang, Jun Chen, Guang-lu Shi in Solar Physics (2024)

  6. Article

    Open Access

    Unraveling the energy storage mechanism in graphene-based nonaqueous electrochemical capacitors by gap-enhanced Raman spectroscopy

    Graphene has been extensively utilized as an electrode material for nonaqueous electrochemical capacitors. However, a comprehensive understanding of the charging mechanism and ion arrangement at the graphene/e...

    **ao-Ting Yin, En-Ming You, Ru-Yu Zhou, Li-Hong Zhu, Wei-Wei Wang in Nature Communications (2024)

  7. No Access

    Article

    Plant regeneration in the new era: from molecular mechanisms to biotechnology applications

    Plants or tissues can be regenerated through various pathways. Like animal regeneration, cell totipotency and pluripotency are the molecular basis of plant regeneration. Detailed systematic studies on Arabidopsis...

    Chunli Chen, Yuxin Hu, Momoko Ikeuchi, Yuling Jiao in Science China Life Sciences (2024)

  8. Article

    Open Access

    PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3

    The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...

    Jia-Teng Sun, Zi-Mu Wang, Liu-Hua Zhou, Tong-Tong Yang, Di Zhao in Communications Biology (2024)

  9. No Access

    Article

    Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications

    Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial, spectral and p...

    Jian-Bin Zhang, Nan Zhou, Li-Hui Zhang, Cong-Hui Shang, Jia-Xuan Li, Yi Zhao in Rare Metals (2024)

  10. Article

    Open Access

    PI3K/AKT/mTOR signaling pathway: an important driver and therapeutic target in triple-negative breast cancer

    Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. It has higher ag...

    Huan-** Zhang, Rui-yuan Jiang, Jia-yu Zhu, Ke-na Sun, Yuan Huang in Breast Cancer (2024)

  11. Article

    Open Access

    Radiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells

    Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...

    Jia-zheng Jiao, Yang Zhang, Wen-juan Zhang, Min-di He in Acta Pharmacologica Sinica (2024)

  12. No Access

    Article

    Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial

    Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the ...

    Jian-Shun Zhou, Zhen Chen, Ying-Ying Liu, Mao-Lin Zhong, Qiong Zhong, Jun Wei in CNS Drugs (2024)

  13. No Access

    Article

    Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics

    The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large a...

    Yi-Tong Zhou, Pei-Jie Zhang, Shu-** Wang, Chang-Hao Li in Toxicological Research (2024)

  14. No Access

    Article

    Singular spectrum analysis based slee** stage classification via electrooculogram

    The slee** stage classification plays an important role in the medical science because it helps the diagnosis of the mental health diseases. The conventional approach for performing the slee** stage classi...

    Jia-Hui Che, Bingo Wing-Kuen Ling, Xueling Zhou in Multimedia Tools and Applications (2024)

  15. No Access

    Article

    A novel AIE-based mitochondria-targeting fluorescent probe for monitoring of the fluctuation of endogenous hypochlorous acid in ferroptosis models

    Ferroptosis is a way of cell death mainly due to the imbalance between the production and degradation of lipid reactive oxygen species, which is closely associated with various diseases. Endogenous hypochlorou...

    Jia Li, Zhiqiang Yang, Wenya Yang, Xuan Zhao in Analytical and Bioanalytical Chemistry (2024)

  16. Article

    Open Access

    Measurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector

    Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...

    G. Aad, E. Aakvaag, B. Abbott, S. Abdelhameed, K. Abeling in Journal of High Energy Physics (2024)

  17. Article

    Open Access

    Chiral quantum heating and cooling with an optically controlled ion

    Quantum heat engines and refrigerators are open quantum systems, whose dynamics can be well understood using a non-Hermitian formalism. A prominent feature of non-Hermiticity is the existence of exceptional po...

    **-Tao Bu, Jian-Qi Zhang, Ge-Yi Ding, Jia-Chong Li in Light: Science & Applications (2024)

  18. Article

    Open Access

    Development and validation of a machine learning predictive model for perioperative myocardial injury in cardiac surgery with cardiopulmonary bypass

    Perioperative myocardial injury (PMI) with different cut-off values has showed to be associated with different prognostic effect after cardiac surgery. Machine learning (ML) method has been widely used in peri...

    Qian Li, Hong Lv, Yuye Chen, **gjia Shen, Jia shi in Journal of Cardiothoracic Surgery (2024)

  19. No Access

    Article

    Characterization of Gut Microbiota in Rats and Rhesus Monkeys After Methamphetamine Self-administration

    Methamphetamine (MA) is one of the most abused drugs globally, but the mechanism of its addiction remains unclear. Several animal studies have shown that the gut microbiota (GM) influences addictive behaviors,...

    Li He, Jia-hui Zhou, Huan Li, Wen-lei Zhang, Tie-qiao Liu in Molecular Neurobiology (2024)

  20. Article

    Open Access

    A novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension

    Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...

    Jia-zhou Ye, Hua-ze Lu, Can Zeng, Guo Lei, **ao-bo Wang, Jie Chen, Tao Bai in BMC Cancer (2024)

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