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2,926 Result(s)
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Article
Open AccessTargeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma
Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...
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SoccerNet 2023 challenges results
The SoccerNet 2023 challenges were the third annual video understanding challenges organized by the SoccerNet team. For this third edition, the challenges were composed of seven vision-based tasks split into t...
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Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages
Liver X receptors (LXRs) which link lipid metabolism and inflammation, were overexpressed in experimental rheumatoid arthritis (RA) rats as observed in our previous studies, while suppression of LXRα by silybi...
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In situ revealing C–C coupling behavior for CO2 electroreduction on tensile strain Ptδ+–Cuδ+ dual sites
Engineering the desired dual metal sites to realize C–C coupling of CO2 is of great importance for the practical applications of CO2 electroreduction reaction (CER). Herein, an efficient strategy for constructing...
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Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Open AccessUnraveling the energy storage mechanism in graphene-based nonaqueous electrochemical capacitors by gap-enhanced Raman spectroscopy
Graphene has been extensively utilized as an electrode material for nonaqueous electrochemical capacitors. However, a comprehensive understanding of the charging mechanism and ion arrangement at the graphene/e...
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Plant regeneration in the new era: from molecular mechanisms to biotechnology applications
Plants or tissues can be regenerated through various pathways. Like animal regeneration, cell totipotency and pluripotency are the molecular basis of plant regeneration. Detailed systematic studies on Arabidopsis...
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Open AccessPEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3
The peroxisome is a versatile organelle that performs diverse metabolic functions. PEX3, a critical regulator of the peroxisome, participates in various biological processes associated with the peroxisome. Whe...
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Optical and electrical anisotropy regulation engineering of low-dimensional materials toward polarized detection and imaging applications
Polarized-sensitive image sensors are a kind of photodetector with great development potential due to their enhanced ability to detect and identify the target objects from the aspect of spatial, spectral and p...
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Open AccessPI3K/AKT/mTOR signaling pathway: an important driver and therapeutic target in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a highly heterogeneous tumor lacking estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression. It has higher ag...
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Open AccessRadiofrequency radiation reshapes tumor immune microenvironment into antitumor phenotype in pulmonary metastatic melanoma by inducing active transformation of tumor-infiltrating CD8+ T and NK cells
Immunosuppression by the tumor microenvironment is a pivotal factor contributing to tumor progression and immunotherapy resistance. Priming the tumor immune microenvironment (TIME) has emerged as a promising s...
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Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial
Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the ...
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Biosafety assessments of hexafluoropropylene trimer derivative as a fluorinated cooling fluid for electronics
The Internet Data Center (IDC) is one of the most important infrastructures in the field of information technology. The cooling system for heat dissipation of IDC is indispensable due to it generates a large a...
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Singular spectrum analysis based slee** stage classification via electrooculogram
The slee** stage classification plays an important role in the medical science because it helps the diagnosis of the mental health diseases. The conventional approach for performing the slee** stage classi...
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A novel AIE-based mitochondria-targeting fluorescent probe for monitoring of the fluctuation of endogenous hypochlorous acid in ferroptosis models
Ferroptosis is a way of cell death mainly due to the imbalance between the production and degradation of lipid reactive oxygen species, which is closely associated with various diseases. Endogenous hypochlorou...
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Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Open AccessChiral quantum heating and cooling with an optically controlled ion
Quantum heat engines and refrigerators are open quantum systems, whose dynamics can be well understood using a non-Hermitian formalism. A prominent feature of non-Hermiticity is the existence of exceptional po...
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Open AccessDevelopment and validation of a machine learning predictive model for perioperative myocardial injury in cardiac surgery with cardiopulmonary bypass
Perioperative myocardial injury (PMI) with different cut-off values has showed to be associated with different prognostic effect after cardiac surgery. Machine learning (ML) method has been widely used in peri...
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Characterization of Gut Microbiota in Rats and Rhesus Monkeys After Methamphetamine Self-administration
Methamphetamine (MA) is one of the most abused drugs globally, but the mechanism of its addiction remains unclear. Several animal studies have shown that the gut microbiota (GM) influences addictive behaviors,...
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Open AccessA novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension
Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...