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Article
Open AccessSurvival benefit of inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a nationwide cohort study
The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD) is debated. We investigated whether the administration of ICS could lower the mortality risk in patients with COPD. We ...
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Article
Open AccessTranscriptome profiling and characterization of peritoneal metastasis ovarian cancer xenografts in humanized mice
Although immunotherapy has not yet been as successful in ovarian cancer (OC), it remains a potential therapeutic strategy. Preclinical models of OC are necessary to evaluate the efficacy of immuno-oncology (IO...
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Article
Open AccessFermentative aminopyrrolnitrin production by metabolically engineered Corynebacterium glutamicum
Aminopyrrolnitrin (APRN), a natural halogenated phenylpyrrole derivative (HPD), has strong antifungal and antiparasitic activities. Additionally, it showed 2.8-fold increased photostability compared to pyrroln...
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Article
Correlation analysis of cancer stem cell marker CD133 and human endogenous retrovirus (HERV)-K env in SKOV3 ovarian cancer cells
Human endogenous retrovirus (HERV)-K is a type of retrovirus that is present in the human genome, and its expression is usually silenced in healthy tissues. The precise mechanism by which HERV-K env influences ca...
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Article
Open AccessBlood pressure outcomes at 18 months in primary care patients prescribed remote physiological monitoring for hypertension: a prospective cohort study
This pragmatic matched cohort study using EHR data extended the follow up to 18 months for BP outcomes comparing individuals prescribed remote patient monitoring (n = 288) and temporally-matched controls (n = 115...
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Article
Open AccessAssociation between body fat decrease during the first year after diagnosis and the prognosis of idiopathic pulmonary fibrosis: CT-based body composition analysis
The prognostic role of changes in body fat in patients with idiopathic pulmonary fibrosis (IPF) remains underexplored. We investigated the association between changes in body fat during the first year post-dia...
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Article
Prevalence and risk factors of low vitamin D levels in children and adolescents with familial hypokalemic periodic paralysis
Patients with familial hypokalemic periodic paralysis (HOKPP) experience episodes of reversible immobility and are at an increased risk of limited sunlight exposure, potentially leading to vitamin D deficiency...
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Article
Suppression of Leakage Currents in Photo-multiplication Photodetectors with Oxidation-Controlled Metal Interfacial Layer
In this work, we investigate the use of annealed metal oxides in electron blocking layer (EBL) of photo-multiplication organic photodetectors (PM-OPD), to obtain low leakage current, high external quantum effi...
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Attitudes Toward Korean Transgenders from a Survey of National Human Rights Commission
The National Human Rights Commission of South Korea published the report on Hate Discrimination of Transgenders in 2014 and 2020, which showed a reality of various forms of discrimination against sexual minori...
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Article
Open AccessMetabolic changes preceding bladder cancer occurrence among Korean men: a nested case-control study from the KCPS-II cohort
Bladder cancer (BLCA) research in Koreans is still lacking, especially in focusing on the prediction of BLCA. The current study aimed to discover metabolic signatures related to BLCA onset and confirm its pote...
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Open AccessBlood pressure outcomes at 12 months in primary care patients prescribed remote physiological monitoring for hypertension: a prospective cohort study
Remote patient monitoring (RPM) for hypertension enables automatic transmission of blood pressure (BP) and pulse into the electronic health record (EHR), but its effectiveness in primary care is unknown. This ...
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Correction to: Multiple Determinants of Interaction Quality among Childcare Providers
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Article
Open AccessAn Image Turing Test on Realistic Gastroscopy Images Generated by Using the Progressive Growing of Generative Adversarial Networks
Generative adversarial networks (GAN) in medicine are valuable techniques for augmenting unbalanced rare data, anomaly detection, and avoiding patient privacy issues. However, there were limits to generating h...
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Article
Multiple Determinants of Interaction Quality among Childcare Providers
Improving childcare quality is an important goal in South Korea as many infants attend childcare centers. The quality of teacher–child interactions is a common and crucial predictor of childcare quality. Thus,...
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Article
Open AccessIdentification of genes associated with the regulation of cold tolerance and the RNA movement in the grafted apple
In grafted apple, rootstock-derived signals influence scion cold tolerance by initiating physiological changes to survive over the winter. To understand the underlying molecular interactions between scion and ...
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Article
Open Access“The familiar taste of poison”: a qualitative study of multi-level motivations for stimulant use in sexual minority men living in South Florida
In the US, stimulant use is associated with a 3–6 times greater rate of HIV seroconversion in sexual minority men (SMM) than in those who do not use stimulants. Annually, 1 in 3 SMM who HIV seroconvert will be...
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Article
Open AccessShort-term effects of a classroom-based STEAM program using robotic kits on children in South Korea
Despite the recent emphasis on technology and engineering in early childhood education, the importance of teaching relevant concepts in early education has been underappreciated in South Korea. This study exam...
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Article
Open AccessGlutathionylation on RNA-binding proteins: a regulator of liquid‒liquid phase separation in the pathogenesis of amyotrophic lateral sclerosis
RNA-binding proteins (RBPs) containing low-sequence complexity domains mediate the formation of cellular condensates and membrane-less organelles with biological functions via liquid‒liquid phase separation (L...
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Article
Open AccessPrevalence of asthma in preterm and associated risk factors based on prescription data from the Korean National Health Insurance database
We retrospectively analyzed National Health Insurance claims data (January 2002–December 2018) to determine the asthma prevalence and risk factors among preterm infants born in Korea. Patients with asthma were...
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Pathologic etiology and predictors of malignancy in children with cervical lymphadenopathy
