-
Article
Open AccessAnalysis of tumor microenvironment alterations in partially responsive rectal cancer patients treated with neoadjuvant chemoradiotherapy
Achieving a pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (NCRT) remains a challenge for most patients with rectal cancer. Exploring the potential of combining NCRT with immunotherapy ...
-
Article
Open AccessRecombinant therapeutic proteins degradation and overcoming strategies in CHO cells
Mammalian cell lines are frequently used as the preferred host cells for producing recombinant therapeutic proteins (RTPs) having post-translational modified modification similar to those observed in proteins ...
-
Article
Early Aerobic Exercise Promotes Neurological Function Recovery of Rats after Cerebral Ischemia/Reperfusion by Upregulating the Expression of Heat Shock Protein A5
The neuroprotective function of heat shock protein A5 (HSPA5) in ischemic stroke has been confirmed. This study aimed to investigate the effects of early aerobic exercise on neurological function recovery from...
-
Article
Establishment of an immortalized cell line derived from the pupal ovary of Mythimna separata (Lepidoptera: Noctuidae) and identification of the cell source
Determining the source of primary cells is conductive to enriching sufficient cells with immortal potential thereby improving the success rate of establishing cell lines. However, most of the existing insect c...
-
Article
Distance effect characteristic of the matrix attachment region increases recombinant protein expression in Chinese hamster ovary cells
Previously, we have found that the matrix attachment region (MAR) may confer a ‘distance effect’ on transgene expression. This work aims to systematically explore the increased transgene expression in transfec...
-
Article
Location of a conservative hyperplane for cutting plane methods in disjoint bilinear programming
Although several classes of cutting plane methods for deterministically solving disjoint bilinear programming (DBLP) have been proposed, the frequently encountered computational issue regarding the generation ...
-
Article
Open AccessBrain astrocytoma misdiagnosed as anti-NMDAR encephalitis: a case report
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, which is the most common type of autoimmune encephalitis, is caused by the production of autoantibodies against NMDA receptor. Anti-NMDAR encephali...
-
Article
Second-Order Optimality Conditions for Multiobjective Optimization Whose Order Induced by Second-Order Cone
This paper is devoted to develo** first-order necessary, second-order necessary, and second-order sufficient optimality conditions for a multiobjective optimization problem whose order is induced by a finite...
-
Article
Crystallization of poly(l-lactide) in the miscible poly(l-lactide)/poly(vinyl acetate) blend induced by carbon nanotubes
In this work, carbon nanotubes (CNTs) were introduced into miscible poly(l-lactide)/poly(vinyl acetate) (PLLA/PVAc) blend and the crystallization behaviors of PLLA with the presence of PVAc and CNTs are systemati...
-
Article
Open AccessAnti-fungal activity, mechanism studies on α-Phellandrene and Nonanal against Penicillium cyclopium
Essential oils from plants have been reported to have wide spread antimicrobial activity against various bacterial and fungal pathogens, and these include α-Phellandrene, Nonanal and other volatile substances....
-
Article
Degeneracy removal in cutting plane methods for disjoint bilinear programming
Disjoint bilinear programming has appeared in miscellaneous practical applications. Although deterministic approaches such as cutting plane methods for solving it have been proposed, the frequently encountered...
-
Article
Open AccessAntioxidant Activities of Protein Hydrolysates Obtained from the Housefly Larvae
The housefy is an important resource insect and the housefy larvae are ideal source of food additives. The housefy larvae protein hydrolysates were obtained by enzymatic hydrolysis by alcalase and neutral prot...
-
Article
An improved procedure for determining 90Sr in groundwater based on cation-exchange enrichment and solid-phase extraction
An improved procedure was developed using cation exchange enrichment and solid-phase extraction to determine 90Sr in groundwater. Sr desorption from cation exchange column and sorption on Sr-resin column were car...
-
Article
Effect of abiotic stress on the gameophyte of Pyropia katadae var. hemiphylla (Bangiales, Rhodophyta)
Pyropia germplasm qualified for drift system culture is highly applicable in China. The current farmed species are tolerant to abiotic stresses, but vulnerable without air drying. Pyropia...
-
Article
Open AccessNew Anti-angiogenic Leading Structure Discovered in the Fruit of Cimicifuga yunnanensis
Cimyunnins A–C (1–3), characterized with an unusual fused cyclopentenone ring G, together with cimyunnin D (4), possessing a highly rearranged γ-lactone ring F, were characterized from the fruit of Cimicifuga yun...
-
Article
Open AccessLong noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge
Long noncoding RNAs (lncRNAs) have been identified as having functional roles in cancer biology and are deregulated in many cancers. The present study aimed to determine the expression, roles and functional me...
-
Article
Genomic sequence analysis of Helicoverpa armigera nucleopolyhedrovirus isolated from Australia
The complete genomic sequence of Helicoverpa armigera nucleopolyhedrovirus from Australia, HearNPV-Au, was determined and analyzed. The HearNPV-Au genome was 130,992 bp in size with a G + C content of 39 mol% an...
-
Article
Effects of Norepinephrine on Immune Functions of Cultured Splenic Lymphocytes Exposed to Aluminum Trichloride
The aim of this study was to investigate the effect of norepinephrine (NE) on spleen lymphocytes exposed to aluminum trichloride (AlCl3). In this experiment, lymphocytes were isolated from spleens of healthy Wist...
-
Article
Open AccessH.264/SVC parameter optimization based on quantization parameter, MGS fragmentation, and user bandwidth distribution
In the situation of limited bandwidth, how to improve the performance of scalable video coding plays an important role in video coding. The previously proposed scalable video coding optimization schemes concen...
-
Article
Effect of mechanical pre-conditioning on fracture resistance of polypropylene
The effect of externally applied mechanical pre-conditioning, i.e. pre-impact treatment, on the fracture resistance was investigated for polypropylene (PP). Impact strength was obtained via notched and/or unnotch...
