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Article
Open AccessEffects of intravenous inflammasome inhibitor (NuSepin) on suppression of proinflammatory cytokines release induced by cardiopulmonary bypass in swine model: a pilot study
The systemic inflammatory response syndrome can occur due to an inflammatory reaction to the release of cytokines, and it has been linked to the circulation of pro- and anti-inflammatory cytokines. The cardiop...
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Article
Differential ligand binding/trafficking for distinct CTLA-4 fates: is it an expandable mechanism?
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Article
Open AccessDeep learning model to predict Epstein–Barr virus associated gastric cancer in histology
The detection of Epstein–Barr virus (EBV) in gastric cancer patients is crucial for clinical decision making, as it is related with specific treatment responses and prognoses. Despite its importance, the limit...
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Article
Open AccessDepression in public officials during the COVID-19 pandemic in Paraguay: a web-based study
According to the World Health Organization, the coronavirus disease 2019 (COVID-19) pandemic has created situations that have a negative effect on people and threaten their mental health. Paraguay announced th...
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Article
Open AccessDevelopment of a system to support warfarin dose decisions using deep neural networks
The first aim of this study was to develop a prothrombin time international normalized ratio (PT INR) prediction model. The second aim was to develop a warfarin maintenance dose decision support system as a pr...
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Article
A study on the application of laser cleaning process in shipbuilding industries using 100 W fiber laser
To address the limitations of existing surface cleaning technologies in shipyards, various studies are underway to apply the laser cleaning process, which uses a laser as a heat source, to pretreatment for pai...
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Article
Open AccessCOVID-19 screening center models in South Korea
In a recent report, the British Broadcasting Company (BBC) introduced South Korea’s measures to manage COVID-19 as role model for the world. Screening centers serve as frontiers for preventing community transm...
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Article
Open AccessAnalysis of personal and national factors that influence depression in individuals during the COVID-19 pandemic: a web-based cross-sectional survey
The World Health Organization (WHO) declared coronavirus disease (COVID-19) a pandemic on March 11, 2020. Previous studies of infectious diseases showed that infectious diseases not only cause physical damage ...
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Chapter and Conference Paper
Discrimination of Chronic Liver Disease in Non-contrast CT Images using CNN-Deep Learning
Recently, there have been considerable efforts to develop non-invasive image-based method for diagnosis, staging, and monitoring of chronic liver disease (CLD). This study developed a deep learning (DL) algori...
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Chapter and Conference Paper
Development of Web-Based Management System and Dataset for Radiology-Common Data Model (R-CDM) and Its Clinical Application in Liver Cirrhosis
The Observational Medical Outcomes Partnership-Common Data Model (OMOP-CDM) used in distributed research networks has low coverage of clinical data and does not reflect the latest trends of precision medicine....
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Chapter and Conference Paper
Analysis and Classification of Urinary Stones Using Deep Learning Algorithm: A Clinical Application of Radiology-Common Data Model (R-CDM) Data Set
Recent advances in artificial intelligence have been used for a variety of clinical interests, such as lesion detection, segmentation, classification, and differentiation in medical images, and a great deal of...
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Article
Open AccessDevelopment of quantification software for evaluating body composition contents and its clinical application in sarcopenic obesity
In sarcopenic obesity, the importance of evaluating muscle and fat mass is unquestionable. There exist diverse quantification methods for assessing muscle and fat mass by imaging techniques; thus these methods...
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Article
Open AccessAmino acid transporters as tetraspanin TM4SF5 binding partners
Transmembrane 4 L6 family member 5 (TM4SF5) is a tetraspanin that has four transmembrane domains and can be N-glycosylated and palmitoylated. These posttranslational modifications of TM4SF5 enable homophilic or h...
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Article
Open AccessAccuracy of proton magnetic resonance for diagnosing non-alcoholic steatohepatitis: a meta-analysis
Liver biopsy is the reference standard test to differentiate between non-alcoholic steatohepatitis (NASH) and simple steatosis (SS) in non-alcoholic fatty liver disease (NAFLD), but noninvasive diagnostics are...
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Article
Open AccessTM4SF5-mediated CD44v8-10 splicing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis
Reactive oxygen species (ROS) regulate cell fate, although signaling molecules that regulate ROS hormesis remain unclear. Here we show that transmembrane 4 L six family member 5 (TM4SF5) in lung epithelial cel...
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Article
Open AccessDevelopment of liver surface nodularity quantification program and its clinical application in nonalcoholic fatty liver disease
The liver morphological changes in relation to fibrosis stage in nonalcoholic fatty liver disease (NAFLD) have not yet been clearly understood. This study was to develop a liver surface nodularity (LSN) quanti...
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Article
Chitosan-Based Hybrid Nanocomplex for siRNA Delivery and Its Application for Cancer Therapy
Chitosan, a natural and biocompatible cationic polymer, is an attractive carrier for small interfering RNA (siRNA) delivery. The purpose of this study was to develop a chitosan-based hybrid nanocomplex that ex...
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Article
SUMO modification of NZFP mediates transcriptional repression through TBP binding
The negatively regulating zinc finger protein (NZFP) is an essential transcription repressor required for early development during gastrulation in Xenopus laevis. In this study, we found that NZFP interacts wi...
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Chapter and Conference Paper
Security in Underwater Acoustic Sensor Network: Focus on Suitable Encryption Mechanisms
Underwater acoustic sensor network (UWASN) technology is advancing recently, and research is increasing rapidly. UWASN can be applicable to many fields such as underwater monitoring, underwater resource explor...
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Chapter and Conference Paper
Integrated Real-Time Acoustic Communication System for Controlling of Bio-inspired Underwater Robot
Robot control system construction that uses an underwater robot is essential in the oceanic environment. In this paper, we designed a robot system optimized for the underwater environment and proposed a hybrid...
