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Article
Open AccessInjection laryngoplasty of human adipose-derived stem cell spheroids with hyaluronic acid-based hydrogel improves the morphological and functional characteristics of geriatric larynx
As the geriatric population increased, the need of treatment for laryngeal atrophy and dysfunction increased. This study was performed to evaluate the effects of injection of human adipose-derived stem cell (h...
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Article
Precipitation-Mediated PEGylation of Plant-Derived Nanovesicles
Recently, plant-derived nanovesicles have attracted interest in the field of regenerative medicine because of their abundant immune-regulatory RNAs and phytochemicals with cell proliferation activity. However,...
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Article
The Antioxidant Effect of Small Extracellular Vesicles Derived from Aloe vera Peels for Wound Healing
Extracellular vesicles (EVs) derived from plants have emerged as potential candidates for cosmetic and therapeutic applications. In this study, we isolated EVs from Aloe vera peels (A-EVs) and investigated the an...
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Article
Hyaluronic Acid Coating on Hydrophobic Tracheal Scaffold Enhances Mesenchymal Stem Cell Adhesion and Tracheal Regeneration
Long segmental tracheal repair is challenging in regenerative medicine due to low adhesion of stem cells to tracheal scaffolds. Optimal transplantation of stem cells for tracheal defects has not been establish...
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Article
Open AccessTransplantation of a 3D-printed tracheal graft combined with iPS cell-derived MSCs and chondrocytes
For successful tracheal reconstruction, tissue-engineered artificial trachea should meet several requirements, such as biocompatible constructs comparable to natural trachea, coverage with ciliated respiratory...
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Article
Artificial skin models for animal-free testing
Since 2013, as ethics for animal experiments has been strengthened in the European Union, artificial skin models have attracted attention as an alternative to animal testing for assessing the safety and toxici...
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Article
An Electrochemical Biosensor Based on a Myoglobin-specific Binding Peptide for Early Diagnosis of Acute Myocardial Infarction
In this study, a simple, highly sensitive electrochemical biosensor for myoglobin was developed using a myoglobinspecific binding peptide as a sensing probe. A peptide (Myo-3R7, CPSTLGASC, 838 Da) identified b...
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Article
Electrospinning strategies of drug-incorporated nanofibrous mats for wound recovery
Electrospun nanofibrous mats have recently been employed as drug reservoirs for their unique features, such as high surface-to-volume ratios and easy fabrication process. We describe herein various methods of ...
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Article
Molecular imaging for In vivo tracking of stem cell fate
Stem cells have a potential to dramatically change the common modalities of treatment for many diseases. Despite their rapid transition from animal studies to clinical applications, a number of unanswered ques...
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Article
Adipose tissue: A valuable resource of biomaterials for soft tissue engineering
Extracellular matrices (ECMs), isolated through decellularization of mammalian tissues, have been successfully used in a variety of tissue engineering and regenerative medicine applications. The composition an...
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Article
Electrospun Chitosan Microspheres for Complete Encapsulation of Anionic Proteins: Controlling Particle Size and Encapsulation Efficiency
Electrospinning was employed to fabricate chitosan microspheres by a single-step encapsulation of proteins without organic solvents. Chitosan in acetic acid was electrospun toward a grounded sodium carbonate s...
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Article
Recellularization of decellularized human adipose-tissue-derived extracellular matrix sheets with other human cell types
Decellularized human extracellular matrices (ECMs) are an extremely appealing biomaterial for tissue engineering and regenerative medicine. In this study, we decellularized human adipose tissue, fabricated a t...
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Article
Arbitrary, complex cell patterning via inkjet printing of a cell membrane-anchoring polymer
Well-defined cell patterns, including both adherent and non-adherent cells, were created using piezoelectric inkjet printing of a cell membrane-anchoring polymer composed of a hydrophobic oleyl group, a hydrop...
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Article
In vitro expansion of human adipose-derived stem cells in a spinner culture system using human extracellular matrix powders
Stem cell therapy requires large numbers of stem cells to replace damaged tissues, but only limited numbers of stem cells can be harvested from a single patient. To obtain large quantities of stem cells with d...
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Article
A Glucose Sensor Fabricated by Piezoelectric Inkjet Printing of Conducting Polymers and Bienzymes
Piezoelectric inkjet printing of polymers and proteins holds great promise for fabrication of miniaturized bioelectronic devices, such as biochips and biosensors. In this study, a bienzymatic glucose biosensor...
