3,447 Result(s)

Article

Delayed hypersensitivity in alcoholic cirrhosis

Since there is evidence for an increased incidence of infection in patients with alcoholic cirrhosis of the liver, a study was performed to determine whether or not impairment of delayed hypersensitivity react...

Bernard Straus MD, FACP… in The American Journal of Digestive Diseases (1971)

Chapter

Virus-Induced Diabetes Mellitus

Insulin-dependent diabetes mellitus (IDDM), also known as juvenile diabetes, results from destruction of the insulin-producing beta cells in the pancreas [1]. Both viruses and autoimmunity have been suggested ...

Abner Lotus Notkins, Ji-Won Yoon in Concepts in Viral Pathogenesis (1984)

Chapter

Radiologic Diagnosis

Esophagography with barium meal is a simple and sensitive method of diagnosing tumors of the esophagus [1]. It can determine the anatomic location, nature, and extent of the tumor and its relation to the neigh...

Zheng Yan Wang, Ji Hao Su in Carcinoma of the Esophagus and Gastric Cardia (1984)

Chapter

Risk Factors of Primary Liver Cancer in the High Prevalence Area Chongming County; Results from a 5-year Follow-up

Primary liver cancer (PLC) ranks third among all cancer sites in the People’s Republic of China and causes at least 100 000 deaths per year. High mortality areas are concentrated in the east to south coastal r...

Tu Ji-Tao, Gao Ru-Nie, Zhang Dan-Hua… in Cancer of the Liver, Esophagus, and Nasoph… (1987)

Chapter

The Role of Promotion in the Carcinogenesis of Nasopharyngeal Carcinoma

It is well known that evidence for the chemical promotion of cocarcinogenesis was first provided by Berenblum. Subsequently, Mottram, Boutwell, Van Duren, and Hecker were responsible for defining many importan...

Yao Kai-Tai, Wu Peng-Nian, Jiang Ji-Wen in Cancer of the Liver, Esophagus, and Nasopharynx (1987)

Chapter

A Survey of the Familial Aggregation of Esophageal Cancer in Yangcheng County, Shanxi Province

Yangcheng is a mountainous county located at the southern end of the Taihang mountain range in the southeastern part of Shanxi province. It has an area of 1968 km², 24 communes, 451 production brigades, 2251 vill...

Li Guang-Heng, He Li-Ji in Cancer of the Liver, Esophagus, and Nasopharynx (1987)

Article

Abstracts of the sixth international conference on experimental ulcer

P. Aho, I. -B. Lindén, E. Nissinen, P. Pohto… in Digestive Diseases and Sciences (1988)

Article

Combined treatment of autoimmune MRL/Mp-lpr/lpr mice with cholera toxin plus irradiation

MRL/Mp-lpr/lpr (MRL/1) mice spontaneously develop autoimmune diseases like systemic lupus erythematosus (SLE) from 2 months of age, accompanied by massive lymphadenopathy. Such mice of 2 months of age were tre...

Ji-Lao Fan, Kunisuke Himeno, Ashraf Hussain, Kikuo Nomoto in Biotherapy (1989)

Chapter

Stable Isotope-Labeled Tryptophan as a Precursor for Studying the Disposition of Quinolinic Acid in Rabbits

A major pathway for metabolism of the essential amino acid tryptophan via the kynurenine pathway leads to the production of quinolinic acid as a precursor for nicotinamide containing nucleotides (Nishizuka and...

R. L. Boni, M. P. Heyes, J. D. Bacher, J. A. Yergey… in Kynurenine and Serotonin Pathways (1991)

Chapter

Non-Competitive Inhibition of 3-Hydroxyanthranilate-3, 4-Dioxygenase by 4-Chloro-3-Hydroxyanthranilic Acid in Whole Brain of Rat

The catabolism of L-tryptophan through the kynurenine pathway has long been recognized as the predominant route for systemic L-tryptophan metabolism and synthesis of nicotinamide containing nucleotides in mamm...

X.-D. Ji, M. Nishimura, M. P. Heyes in Kynurenine and Serotonin Pathways (1991)

Article

Preliminary result of mixed bacterial vaccine as adjuvant treatment of hepatocellular carcinoma

Mixed bacterial vaccine (MBV) was employed in the multi-modality treatment of hepatocellular carcinoma (HCC) during 1985–1988. Thirty eight patients undergoing palliative resection and cisplatin therapy (Serie...

Zhao You Tang, Hai Yan Zhou, Gang Zhao… in Medical Oncology and Tumor Pharmacotherapy (1991)

Article

Potentiation of the efficacy of murine L1210 leukemia vaccine by a novel immunostimulator 7-thia-8-oxoguanosine: Increased survival after immunization with vaccine plus 7-thia-8-oxoguanosine

We have investigated the ability of a novel immunopotentiator, 7-thia-8-oxoguanosine (7T8OG) to increase the efficacy of a weakly immunogenic murine L1210 leukemia vaccine. The vaccine was prepared by irradiat...

Brahma S. Sharma, Louisa Balazs, Ai **… in Cancer Immunology, Immunotherapy (1991)

Chapter

Treatment of hepatocellular carcinoma: A summary of 33 years’ experience

Hepatocellular carcinoma (HCC), the most common type (90-95%) of primary liver cancer (PLC), causes 100,000 deaths every year in China. However, based on various strategies aimed at controlling this neoplasm, ...

Zhao-You Tang, Ye-Qin Yu, **n-Da Zhou, Bing-Hui Yang… in Primary Liver Cancer in Japan (1992)

Chapter and Conference Paper

Evaluation of Early Detection and Treatment of Hepatocellular Carcinoma

During 1972–1991, 1443 patients with hepatocellular carcinoma (HCC) were studied. Comparison between screening (n=522) and nonscreening (n=921) groups revealed higher small HCC percentage (49.4% vs. 12.4%), hi...

Zhao-You Tang, Ye-Qin Yu, Bing-Hui Yang… in Recent Advances in Management of Digestive… (1993)

Chapter

Oxidant Generation in Mouse Skin in Response to Phorbol Ester Tumor Promoters

Oxygen radicals are believed to play an important role in cellular pathologies such as reperfusion injury, xenobiotic-induced toxicity, and chemically-induced cancer. Strong circumstantial evidence suggests ge...

L. J. Marnett, C. Ji in Eicosanoids and Other Bioactive Lipids in … (1993)

Chapter and Conference Paper

Evaluation of E-Cadherins in Growth Patterns of Gastric Cancer and Its Degree of Cell Differentiation

The growth pattern in gastric cancer (GC) classified into expanding and infiltrative type proposed by professor Ming. This study examined the expression of E-Cadherins (E-Cad), an intercellular adhesion molecu...

Zhi-** Chen, Jian-Chun Chai… in Recent Advances in Management of Digestive… (1993)

Article

Radioimmunotherapy for unresectable hepatocellular carcinoma using¹³¹I-Hepama-1 mAb: preliminary results

Twenty-three patients with surgically verified unresectable hepatocellular carcinoma (HCC) have been treated by intrahepatic arterial administration of¹³¹I-labeled anti-HCC monoclonal antibody (Hepama-1) combined...

Zhao-Chong Zeng, Zhao-You Tang, Hong **e… in Journal of Cancer Research and Clinical On… (1993)

Article

Cytotoxicity, DNA cross-linking, and DNA single-strand breaks induced by cyclophosphamide in a rat leukemia in vivo

A study of cyclophosphamide (CP)-induced DNA damage and repair occurring in vivo was conducted in the brown Norway rat myelocytic leukemia (BNML) model. DNA single-strand breaks (SSB), DNA-DNA interstrand cros...

Ji-Yi Wang, Greg Prorok, William P. Vaughan in Cancer Chemotherapy and Pharmacology (1993)

Article

Recurrence after resection ofα-fetoprotein-positive hepatocellular carcinoma

The long-term prognosis of surgery for hepatocellular carcinoma (HCC) is not yet satisfactory, the main reason being the high recurrence rate. The authors report the results of a long-term follow-up of 308 pat...

**n-Da Zhou, Zhao-You Tang, Ye-Qin Yu… in Journal of Cancer Research and Clinical On… (1994)

Article

Human anti-(murine Ig) antibody responses in patients with hepatocellular carcinoma receiving intrahepatic arterial¹³¹I-labeled Hepama-1 mAb. Preliminary results and discussion

Human anti-(murine Ig) antibody (HAMA) responses were monitored in 32 patients with unresectable hepatocellular carcinoma (HCC) undergoing radioimmunotherapy using¹³¹I-labeled anti-HCC monoclonal antibody (Hepama...

Zhao-Chong Zeng, Zhao-You Tang, Kang-Da Liu, Ji-Zhen Lu… in Cancer Immunology, Immunotherapy (1994)