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Article
Application of spatial-omics to the classification of kidney biopsy samples in transplantation
Improvement of long-term outcomes through targeted treatment is a primary concern in kidney transplant medicine. Currently, the validation of a rejection diagnosis and subsequent treatment depends on the histo...
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Article
Open AccessA cell-free nutrient-supplemented perfusate allows four-day ex vivo metabolic preservation of human kidneys
The growing disparity between the demand for transplants and the available donor supply, coupled with an aging donor population and increasing prevalence of chronic diseases, highlights the urgent need for the...
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Article
Open AccessRenal biopsies from donors with acute kidney injury show different molecular patterns according to the post-transplant function
The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was to identify protein mediators implicated in eithe...
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Article
Open AccessIncidence of idiopathic nephrotic syndrome during the Covid-19 pandemic in the Paris area (France) and in the Netherlands
The aetiology of idiopathic nephrotic syndrome (INS) remains partially unknown. Viral infections have been associated with INS onset. Since we observed fewer first onset INS cases during the Covid-19 pandemic,...
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Article
Open AccessAntineutrophil cytoplasmic antibodies in infective endocarditis: a case report and systematic review of the literature
Infective endocarditis (IE) may be misdiagnosed as ANCA-associated vasculitis (AAV), especially when antineutrophil cytoplasmic antibodies (ANCA) are detected. Distinguishing IE from AAV is crucial to guide th...
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Kidney Transplantation and Diabetic Nephropathy
Posttransplant diabetes mellitus (PTDM) has some unique features discerning it from type 2 diabetes mellitus (T2DM). In general, PTDM fluctuates often in time and is strongly influenced by immunosuppressive dr...
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Article
Open AccessCorrection: Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
Scientific Reports 6: Article number: 38275; published online: 08 December 2016; updated: 15 March 2017 The original version of this Article contained errors in the spelling of the authors Alessandra Tammaro, ...
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Open AccessDonor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation
NLRP3 (NOD-like receptor family, pyrin domain containing 3) is a member of the inflammasome family and is of special interest in renal disease. Experimental studies have shown that Nlrp3 plays a significant ro...
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Article
Total burden of intraplaque hemorrhage in coronary arteries relates to the use of coumarin-type anticoagulants but not platelet aggregation inhibitors
Intraplaque hemorrhage (IPH) is a crucial factor in progression and destabilization of an atherosclerotic plaque. Anti-thromboembolic drugs are widely used as prophylactic treatment against arterial and venous...
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Article
Open AccessHypertension secondary to a periprostatic paraganglioma: case report and review of the literature
Around 10 per cent of catecholamine-secreting tumours can be found outside the adrenal medulla (paraganglioma). We report a case of a functional sporadic paraganglioma that was localized lateral to the prostat...
