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18F-Fluorodeoxyglucose uptake on positron emission tomography/computed tomography is associated with metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma

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  1. Article

    Open Access

    Potential anti-cancer effect of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a novel histone deacetylase inhibitor, for the treatment of thyroid cancer

    Thyroid cancer has been indicated to have a higher global proportion of DNA methylation and a decreased level of histone acetylation. Previous studies showed that histone gene reviser and epigenetic changes ro...

    Seok-Mo Kim, Ki-Cheong Park, Jeong-Yong Jeon, Bup-Woo Kim, Hyeung-Kyoo Kim in BMC Cancer (2015)

  2. Article

    Open Access

    The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells

    Recent reports using metabolism regulating drugs showed that nutrient deprivation was an efficient tool to suppress cancer progression. In addition, autophagy control is emerging to prevent cancer cell surviva...

    Jeong Yong Jeon, Seung Won Kim, Ki Cheong Park, Mi** Yun in BMC Cancer (2015)

  3. Article

    Open Access

    The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells

    Epigenetic modifications play a critical role in the regulation of all DNA-based processes, such as transcription, repair, and replication. Inappropriate histone modifications can result in dysregulation of ce...

    Ki Cheong Park, Jun Hyeok Heo, Jeong Yong Jeon, Hye Ji Choi, A Ra Jo in BMC Cancer (2015)

  4. Article

    Open Access

    Migration of human neural stem cells toward an intracranial glioma

    Many in vivo and in vitro studies have demonstrated the targeted migration of neural stem cells (NSC) to infiltrating brain tumors, including malignant glioma, highlighting a potential therapeutic approach. Howev...

    Jeong Yong Jeon, Jeung Hee An, Seung Up Kim in Experimental & Molecular Medicine (2008)