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Article
Interstitielle Lungenanomalien
Interstitielle Lungenanomalien („interstitial lung abnormalities“, ILA) sind Zufallsbefunde in der Computertomographie (CT), insbesondere bei älteren Patienten und Rauchern. Sie bezeichnen mögliche frühe inter...
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Article
Lungenkrebsscreening: neue Horizonte
Lungenkrebs ist die häufigste Krebstodesursache weltweit. In den frühen, symptomlosen Stadien ist eine kurative Behandlung möglich, allerdings wird die Erkrankung oft zu spät diagnostiziert.
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Article
Open AccessAlveolar membrane and capillary function in COVID-19 convalescents: insights from chest MRI
To investigate potential presence and resolution of longer-term pulmonary diffusion limitation and microvascular perfusion impairment in COVID-19 convalescents.
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Article
Open AccessEffect of CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor on pulmonary ventilation derived by 3D phase-resolved functional lung MRI in cystic fibrosis patients
To investigate whether 3D phase-resolved functional lung (PREFUL)-MRI parameters are suitable to measure response to elexacaftor/tezacaftor/ivacaftor (ETI) therapy and their association with clinical outcomes ...
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Article
Open AccessCerebral microcirculatory pulse wave propagation and pulse wave amplitude map** in retrospectively gated MRI
To analyze cerebral arteriovenous pulse propagation and to generate phase-resolved pulse amplitude maps from a fast gradient-echo sequence offering flow-related enhancement (FREE). Brain MRI was performed usin...
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Living Reference Work Entry In depth
Grundlagen der radiologischen Diagnostik in der Pneumologie
Mittels radiologischer Methoden können die Lunge und das Mediastinum bildgebend dargestellt und Pathologien detektiert sowie beurteilt werden. Die Bildgebung hat damit einen wichtigen Stellenwert in der pneumo...
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Article
Open AccessDynamic contrast enhanced MRI of pulmonary adenocarcinomas for early risk stratification: higher contrast uptake associated with response and better prognosis
To explore the prognostic value of serial dynamic contrast-enhanced (DCE) MRI in patients with advanced pulmonary adenocarcinoma undergoing first-line therapy with either tyrosine-kinase inhibitors (TKI) or pl...
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Article
Open AccessAssociation of radiological lung pattern and respiratory mechanics with potential for lung recruitment in patients with COVID–ARDS: a retrospective cohort study
The ventilatory management of COVID–ARDS is controversial, especially with regard to the different subtypes and associated PEEP titration. A higher PEEP may be beneficial only in patients with potential for lu...
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Article
Open AccessIncreased regional ventilation as early imaging marker for future disease progression of interstitial lung disease: a feasibility study
Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and a highly variable course. Pathologically increased ventilation—accessible by functional CT—is discussed as a potential predecessor of ...
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Article
Röntgen-Thorax: Durchführung und Indikationen
Die Röntgenübersichtsaufnahme des Thorax ist ungeachtet ihrer mehr als 100-jährigen Geschichte immer noch eine wichtige Technik, um wesentliche Pathologien von Lunge, Herz und Gefäßen schnell und dosissparend ...
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Article
Bildgebung bei pulmonaler Hypertonie
Die pulmonale Hypertonie (PH) ist eine hämodynamische Störung des Lungenkreislaufs mit einer pathologischen Erhöhung des pulmonalarteriellen Drucks.
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Article
Open AccessQuantification of dual-energy CT-derived functional parameters as potential imaging markers for progression of idiopathic pulmonary fibrosis
The individual course of disease in idiopathic pulmonary fibrosis (IPF) is highly variable. Assessment of disease activity and prospective estimation of disease progression might have the potential to improve ...
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Article
Open AccessThe current status and further prospects for lung magnetic resonance imaging in pediatric radiology
Lung MRI makes it possible to replace up to 90% of CT examinations with radiation-free magnetic resonance diagnostics of the lungs without suffering any diagnostic loss. The individual radiation exposure can t...
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Article
Advanced imaging in pulmonary hypertension: emerging techniques and applications
Pulmonary hypertension (PH) is a pathophysiological disorder defined by an increase in pulmonary arterial pressure which can occur in multiple clinical conditions. Irrespective of etiology, PH entails a negati...
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Article
Cardio-pulmonary MRI for detection of treatment response after a single BPA treatment session in CTEPH patients
Chronic thromboembolic pulmonary hypertension (CTEPH) can be treated with balloon pulmonary angioplasty (BPA) in inoperable patients. Sensitive non-invasive imaging methods are missing to detect treatment resp...
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Article
Open AccessBromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction
Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at dif...
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Chapter
Pneumonia
Pneumonia is the most common infectious disease worldwide (Lopez and Murray 1998). The frequency of community-acquired pneumonia in Germany is estimated at 400,000–600,000 patients each year and about 200,000 ...
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Chapter
Fluorinated-Gas MRI
Fluorinated-gas MRI for ventilation imaging is an alternative approach to hyperpolarized-gas MRI using 3He or 129Xe, which may have the potential to be translated into clinical routine in the future. Although in ...
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Article
Open AccessTrade-off between benefits, harms and economic efficiency of low-dose CT lung cancer screening: a microsimulation analysis of nodule management strategies in a population-based setting
In lung cancer screening, a nodule management protocol describes nodule assessment and thresholds for nodule size and growth rate to identify patients who require immediate diagnostic evaluation or additional ...
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Article
Airway remodelling in the transplanted lung
Following lung transplantation, fibrotic remodelling of the small airways has been recognized for almost 5 decades as the main correlate of chronic graft failure and a major obstacle to long-term survival. Mai...