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  1. No Access

    Article

    Interstitielle Lungenanomalien

    Interstitielle Lungenanomalien („interstitial lung abnormalities“, ILA) sind Zufallsbefunde in der Computertomographie (CT), insbesondere bei älteren Patienten und Rauchern. Sie bezeichnen mögliche frühe inter...

    Prof. Dr. Sabine Dettmer, Jens Vogel-Claussen in Die Radiologie (2024)

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    Article

    Lungenkrebsscreening: neue Horizonte

    Lungenkrebs ist die häufigste Krebstodesursache weltweit. In den frühen, symptomlosen Stadien ist eine kurative Behandlung möglich, allerdings wird die Erkrankung oft zu spät diagnostiziert.

    Rimma Kondrashova, Jens Vogel-Claussen in Die Radiologie (2024)

  3. Article

    Open Access

    Alveolar membrane and capillary function in COVID-19 convalescents: insights from chest MRI

    To investigate potential presence and resolution of longer-term pulmonary diffusion limitation and microvascular perfusion impairment in COVID-19 convalescents.

    Agilo Luitger Kern, Isabell Pink, Agnes Bonifacius, Till Kaireit in European Radiology (2024)

  4. Article

    Open Access

    Effect of CFTR modulator therapy with elexacaftor/tezacaftor/ivacaftor on pulmonary ventilation derived by 3D phase-resolved functional lung MRI in cystic fibrosis patients

    To investigate whether 3D phase-resolved functional lung (PREFUL)-MRI parameters are suitable to measure response to elexacaftor/tezacaftor/ivacaftor (ETI) therapy and their association with clinical outcomes ...

    Filip Klimeš, Andreas Voskrebenzev, Marcel Gutberlet, Milan Speth in European Radiology (2024)

  5. Article

    Open Access

    Cerebral microcirculatory pulse wave propagation and pulse wave amplitude map** in retrospectively gated MRI

    To analyze cerebral arteriovenous pulse propagation and to generate phase-resolved pulse amplitude maps from a fast gradient-echo sequence offering flow-related enhancement (FREE). Brain MRI was performed usin...

    Norman Kornemann, Filip Klimeš, Agilo Luitger Kern, Lea Behrendt in Scientific Reports (2023)

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    Living Reference Work Entry In depth

    Grundlagen der radiologischen Diagnostik in der Pneumologie

    Mittels radiologischer Methoden können die Lunge und das Mediastinum bildgebend dargestellt und Pathologien detektiert sowie beurteilt werden. Die Bildgebung hat damit einen wichtigen Stellenwert in der pneumo...

    Sabine Dettmer, Jens Vogel-Claussen in DGIM Innere Medizin

  7. Article

    Open Access

    Dynamic contrast enhanced MRI of pulmonary adenocarcinomas for early risk stratification: higher contrast uptake associated with response and better prognosis

    To explore the prognostic value of serial dynamic contrast-enhanced (DCE) MRI in patients with advanced pulmonary adenocarcinoma undergoing first-line therapy with either tyrosine-kinase inhibitors (TKI) or pl...

    Stephan Rheinheimer, Petros Christopoulos, Stella Erdmann in BMC Medical Imaging (2022)

  8. Article

    Open Access

    Association of radiological lung pattern and respiratory mechanics with potential for lung recruitment in patients with COVID–ARDS: a retrospective cohort study

    The ventilatory management of COVID–ARDS is controversial, especially with regard to the different subtypes and associated PEEP titration. A higher PEEP may be beneficial only in patients with potential for lu...

    Hans-Jörg Gillmann, Carolin Jung, Milan Speth in European Journal of Medical Research (2022)

  9. Article

    Open Access

    Increased regional ventilation as early imaging marker for future disease progression of interstitial lung disease: a feasibility study

    Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and a highly variable course. Pathologically increased ventilation—accessible by functional CT—is discussed as a potential predecessor of ...

    Sarah C. Scharm, Cornelia Schaefer-Prokop, Moritz Willmann in European Radiology (2022)

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    Article

    Röntgen-Thorax: Durchführung und Indikationen

    Die Röntgenübersichtsaufnahme des Thorax ist ungeachtet ihrer mehr als 100-jährigen Geschichte immer noch eine wichtige Technik, um wesentliche Pathologien von Lunge, Herz und Gefäßen schnell und dosissparend ...

    Prof. Dr. Sebastian Ley, Jürgen Biederer, Julia Ley-Zaporozhan in Der Radiologe (2022)

  11. No Access

    Article

    Bildgebung bei pulmonaler Hypertonie

    Die pulmonale Hypertonie (PH) ist eine hämodynamische Störung des Lungenkreislaufs mit einer pathologischen Erhöhung des pulmonalarteriellen Drucks.

    PD Dr. Fabian Rengier, Claudius Melzig, Jens Vogel-Claussen in Der Pneumologe (2021)

  12. Article

    Open Access

    Quantification of dual-energy CT-derived functional parameters as potential imaging markers for progression of idiopathic pulmonary fibrosis

    The individual course of disease in idiopathic pulmonary fibrosis (IPF) is highly variable. Assessment of disease activity and prospective estimation of disease progression might have the potential to improve ...

    Sarah C. Scharm, Jens Vogel-Claussen, Cornelia Schaefer-Prokop in European Radiology (2021)

  13. Article

    Open Access

    The current status and further prospects for lung magnetic resonance imaging in pediatric radiology

    Lung MRI makes it possible to replace up to 90% of CT examinations with radiation-free magnetic resonance diagnostics of the lungs without suffering any diagnostic loss. The individual radiation exposure can t...

    Franz Wolfgang Hirsch, Ina Sorge, Jens Vogel-Claussen in Pediatric Radiology (2020)

  14. No Access

    Article

    Advanced imaging in pulmonary hypertension: emerging techniques and applications

    Pulmonary hypertension (PH) is a pathophysiological disorder defined by an increase in pulmonary arterial pressure which can occur in multiple clinical conditions. Irrespective of etiology, PH entails a negati...

    Fabian Rengier, Claudius Melzig in The International Journal of Cardiovascula… (2019)

  15. No Access

    Article

    Cardio-pulmonary MRI for detection of treatment response after a single BPA treatment session in CTEPH patients

    Chronic thromboembolic pulmonary hypertension (CTEPH) can be treated with balloon pulmonary angioplasty (BPA) in inoperable patients. Sensitive non-invasive imaging methods are missing to detect treatment resp...

    Christian Schoenfeld, Jan B. Hinrichs, Karen M. Olsson in European Radiology (2019)

  16. Article

    Open Access

    Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction

    Right ventricular (RV) dysfunction predicts adverse outcome in peripartum cardiomyopathy (PPCM). We recently demonstrated beneficial effects associated with the prolactin release inhibitor bromocriptine at dif...

    Arash Haghikia, Johannes Schwab, Jens Vogel-Claussen in Clinical Research in Cardiology (2019)

  17. No Access

    Chapter

    Pneumonia

    Pneumonia is the most common infectious disease worldwide (Lopez and Murray 1998). The frequency of community-acquired pneumonia in Germany is estimated at 400,000–600,000 patients each year and about 200,000 ...

    Sabine Dettmer, Jens Vogel-Claussen in Multislice CT (2019)

  18. No Access

    Chapter

    Fluorinated-Gas MRI

    Fluorinated-gas MRI for ventilation imaging is an alternative approach to hyperpolarized-gas MRI using 3He or 129Xe, which may have the potential to be translated into clinical routine in the future. Although in ...

    Marcel Gutberlet, Jens Vogel-Claussen in MRI of the Lung (2018)

  19. Article

    Open Access

    Trade-off between benefits, harms and economic efficiency of low-dose CT lung cancer screening: a microsimulation analysis of nodule management strategies in a population-based setting

    In lung cancer screening, a nodule management protocol describes nodule assessment and thresholds for nodule size and growth rate to identify patients who require immediate diagnostic evaluation or additional ...

    Marina Treskova, Ines Aumann, Heiko Golpon, Jens Vogel-Claussen in BMC Medicine (2017)

  20. No Access

    Article

    Airway remodelling in the transplanted lung

    Following lung transplantation, fibrotic remodelling of the small airways has been recognized for almost 5 decades as the main correlate of chronic graft failure and a major obstacle to long-term survival. Mai...

    Mark Kuehnel, Lavinia Maegel, Jens Vogel-Claussen in Cell and Tissue Research (2017)

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