4 Result(s)
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Article
Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response
Infants and young children are particularly susceptible to viral encephalitis; however, the mechanisms are unknown. We determined the age-dependent contribution of innate and adaptive immune functions to reovi...
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Article
Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain
Zika virus infection of pregnant nonhuman primates results in the loss of fetal neuronal progenitor cells, even in the absence of overt microcephaly.
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Article
Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate
New animal models of Zika virus (ZIKV) infection are imperative to accelerating efforts to treat or prevent disease in humans. Adams Waldorf et al. now report that ZIKV infection of a pregnant female pigtailed ma...
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Article
The sweet spot: defining virus–sialic acid interactions
Many viruses engage sialylated glycans to bind to and infect cells. Sialic acid-binding viruses include influenza virus, reovirus, adenovirus and rotavirus, wh...
