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    Article

    Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis

    Frailty is classically associated with advanced age but is also an important predictor of clinical outcomes in comparatively young adults with cirrhosis. We examined the association of biological aging with fr...

    Sara C. LaHue, Matias Fuentealba, Stephanie Roa Diaz, Srilakshmi Seetharaman in GeroScience (2024)

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    Article

    Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis

    Kidney dysfunction is associated with increased mortality among patients with cirrhosis. We investigated whether kidney dysfunction types [e.g., acute kidney injury (AKI), chronic kidney disease (CKD), and AKI...

    Giuseppe Cullaro, Jessica B. Rubin, Brett E. Fortune in Digestive Diseases and Sciences (2022)

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    Article

    Visceral Adipose Tissue Inflammation and Radiographic Visceral-to-Subcutaneous Adipose Tissue Ratio in Patients with Cirrhosis

    Accumulation of visceral adipose tissue is associated with hepatic inflammation and fibrosis, suggestive of its metabolic and inflammatory properties. We aimed to examine the histologic findings of visceral an...

    Nghiem B. Ha, Soo-** Cho, Yara Mohamad, Dorothea Kent in Digestive Diseases and Sciences (2022)

  4. Article

    The bidirectional relationship between nonalcoholic fatty liver disease and sarcopenia

    Nghiem B. Ha, Jennifer C. Lai in Hepatology International (2022)

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    Article

    Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax

    Hepatic hydrothorax (HH) remains a difficult-to-treat complication of cirrhosis.

    Jacqueline G. O’Leary, K. Rajender Reddy, Puneeta Tandon in Digestive Diseases and Sciences (2021)

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    Article

    Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates

    Patients with end-stage liver disease awaiting liver transplantation (LT) are seriously ill and experience fluctuating periods of clinical decompensation. Discussion of a patient’s advance care planning (ACP) ...

    Connie W. Wang, Adrienne Lebsack, Rebecca L. Sudore in Digestive Diseases and Sciences (2021)

  7. Article

    Open Access

    Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial

    A randomized trial of a pedometer-based intervention with weekly activity goals led to a modest increase in step count among dialysis patients. In a secondary analysis, we investigated the effect of this inter...

    Anoop Sheshadri, Piyawan Kittiskulnam, Jennifer C. Lai in BMC Nephrology (2020)

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    Article

    Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation

    Impaired physical capacity increases peri-liver transplant complications. Patient perceptions regarding exercise prior to transplantation are not known.

    David M. Chascsa, Jennifer C. Lai, Michael A. Dunn in Digestive Diseases and Sciences (2018)

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    Article

    Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease

    Low medication adherence is known to contribute to worse health outcomes in the general population.

    Selena Z. Kuo, Marta Haftek, Jennifer C. Lai in Digestive Diseases and Sciences (2017)

  10. Article

    Open Access

    Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis

    The Short Physical Performance Battery (SPPB) is a well-established tool to assess lower extremity physical performance status. Its predictive ability for all-cause mortality has been sparsely reported, but wi...

    Rita Pavasini, Jack Guralnik, Justin C. Brown, Mauro di Bari, Matteo Cesari in BMC Medicine (2016)

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    Article

    Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C

    Whether chronic HCV, a disease characterized by systemic inflammation, impacts bone mineral density (BMD) independent of cirrhosis is unknown.

    Jennifer C. Lai, Dolores M. Shoback, Jacob Zipperstein in Digestive Diseases and Sciences (2015)