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Article
Open AccessMulti-domain biopsychosocial postoperative recovery trajectories associate with patient outcomes following lumbar fusion
The purpose of this study is to describe and assess the impact of multi-domain biopsychosocial (BPS) recovery on outcomes following lumbar spine fusion. We hypothesized that discrete patterns of BPS recovery (...
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Article
Open AccessComparison of paraspinal muscle composition measurements using IDEAL fat–water and T2-weighted MR images
The purpose of this study was to evaluate the agreement between paraspinal muscle composition measurements obtained from fat–water images using % fat-signal fraction (%FSF) in comparison to those obtained from...
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Article
Open AccessSpatial distribution of fat infiltration within the paraspinal muscles: implications for chronic low back pain
Fat infiltration (FI) of the paraspinal muscles (PSMs) measured using MRI is an aspect of muscle quality and is considered to be worse in chronic low back pain (cLBP) patients. However, there is not a clear as...
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Article
Open AccessUsing hierarchical unsupervised learning to integrate and reduce multi-level and multi-paraspinal muscle MRI data in relation to low back pain
The paraspinal muscles (PSM) are a key feature potentially related to low back pain (LBP), and their structure and composition can be quantified using MRI. Most commonly, quantifying PSM measures across indivi...
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Article
Open AccessCompensatory biomechanics and spinal loading during dynamic maneuvers in patients with chronic low back pain
This study explores the biomechanics underlying the sit-to-stand (STS) functional maneuver in chronic LBP patients to understand how different spinal disorders and levels of pain severity relate to unique comp...
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Article
Open AccessClinical outcomes one year after a digital musculoskeletal (MSK) program: an observational, longitudinal study with nonparticipant comparison group
The evidence base for the impact of digital health on musculoskeletal (MSK) outcomes is growing, but it is unclear how much digital MSK programs address pain and function in the intermediate and long term.
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Article
Open AccessMeasurement of vertebral endplate bone marrow lesion (Modic change) composition with water–fat MRI and relationship to patient-reported outcome measures
Vertebral endplate bone marrow lesions (“Modic changes”, MC) are associated with chronic low back pain (CLBP). Bone marrow composition in MC is poorly understood. The goals of this study were to: (1) measure b...
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Article
Open AccessISSLS PRIZE IN BIOENGINEERING SCIENCE 2019: biomechanical changes in dynamic sagittal balance and lower limb compensatory strategies following realignment surgery in adult spinal deformity patients
A longitudinal cohort study.
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Article
Open AccessRandomized controlled trial of a 12-week digital care program in improving low back pain
Low back pain (LBP) is the leading cause of disability throughout the world and is economically burdensome. The recommended first line treatment for non-specific LBP is non-invasive care. A digital care progra...
