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Open AccessA comprehensive collection of systems biology data characterizing the host response to viral infection
The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This...
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Inferring Molecular Interactions Pathways from eQTL Data
Analysis of expression quantitative trait loci (eQTL) helps elucidate the connection between genotype, gene expression levels, and phenotype. However, standard statistical genetics can only attribute the chang...
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Computational Representation of Biological Systems
Integration of large and diverse biological data sets is a daunting problem facing systems biology researchers. Exploring the complex issues of data validation, integration, and representation, we present a sy...
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Prediction and Integration of Regulatory and Protein–Protein Interactions
Knowledge of transcriptional regulatory interactions (TRIs) is essential for exploring functional genomics and systems biology in any organism. While several results from genome-wide analysis of transcriptiona...
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The Bioverse API and Web Application
The Bioverse is a framework for creating, warehousing and presenting biological information based on hierarchical levels of organisation. The framework is guided by a deeper philosophy of desiring to represent...
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Open AccessINTEGRATOR: interactive graphical search of large protein interactomes over the Web
The rapid growth of protein interactome data has elevated the necessity and importance of network analysis tools. However, unlike pure text data, network search spaces are of exponential complexity. This poses...
