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Open AccessAuthor Correction: RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessMemory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients
T cells targeting shared oncogenic mutations can induce durable tumor regression in epithelial cancer patients. Such T cells can be detected in tumor infiltrating lymphocytes, but whether such cells can be det...
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Article
Open AccessRGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells
Analysis of 501 melanoma exomes revealed RGS7, which encodes a GTPase-accelerating protein (GAP), to be a tumor-suppressor gene. RGS7 was mutated in 11% of melanomas and was found to harbor three recurrent mutati...
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Identification of essential genes for cancer immunotherapy
Somatic gene mutations can alter the vulnerability of cancer cells to T-cell-based immunotherapies. Here we perturbed genes in human melanoma cells to mimic loss-of-function mutations involved in resistance to...