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Open AccessGenome-wide association and genotype by environment interactions for growth traits in U.S. Red Angus cattle
Genotypic information produced from single nucleotide polymorphism (SNP) arrays has routinely been used to identify genomic regions associated with complex traits in beef and dairy cattle. Herein, we assembled...
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Article
Open AccessGenome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle
Single nucleotide polymorphism (SNP) arrays have facilitated discovery of genetic markers associated with complex traits in domestic cattle; thereby enabling modern breeding and selection programs. Genome-wide...
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Article
Open AccessQTL-map** and genomic prediction for bovine respiratory disease in U.S. Holsteins using sequence imputation and feature selection
National genetic evaluations for disease resistance do not exist, precluding the genetic improvement of cattle for these traits. We imputed BovineHD genotypes to whole genome sequence for 2703 Holsteins that w...
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Article
Open AccessCandidate lethal haplotypes and causal mutations in Angus cattle
If unmanaged, high rates of inbreeding in livestock populations adversely impact their reproductive fitness. In beef cattle, historical selection strategies have increased the frequency of several segregating ...
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Article
Open AccessGenome-wide association study for feed efficiency and growth traits in U.S. beef cattle
Single nucleotide polymorphism (SNP) arrays for domestic cattle have catalyzed the identification of genetic markers associated with complex traits for inclusion in modern breeding and selection programs. Usin...
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Article
Open AccessWhat’s in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual
Next-generation sequencing projects commonly commence by aligning reads to a reference genome assembly. While improvements in alignment algorithms and computational hardware have greatly enhanced the efficienc...
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Article
Open AccessGlobal liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes
Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock ...
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Open AccessQTLs associated with dry matter intake, metabolic mid-test weight, growth and feed efficiency have little overlap across 4 beef cattle studies
The identification of genetic markers associated with complex traits that are expensive to record such as feed intake or feed efficiency would allow these traits to be included in selection programs. To identi...
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Open AccessDetection of selective sweeps in cattle using genome-wide SNP data
The domestication and subsequent selection by humans to create breeds and biological types of cattle undoubtedly altered the patterning of variation within their genomes. Strong selection to fix advantageous l...
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Open AccessA novel analytical method, Birth Date Selection Map**, detects response of the Angus (Bos taurus) genome to selection on complex traits
Several methods have recently been developed to identify regions of the genome that have been exposed to strong selection. However, recent theoretical and empirical work suggests that polygenic models are requ...