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Article
Applications of major histocompatibility complex class I molecules expressed as single chains
Generation of CD8 T-cell responses to pathogens and tumors requires optimal expression of class I major histocompatibility complex/peptide complexes, which, in turn, is dependent on host cellular processing ev...
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Peptide ligand-induced conformation and surface expression of the Ld class I MHC molecule
NEWLY synthesized major histocompatibility complex (MHC) class I molecules in the endoplasmic reticulum are thought to bind peptides of foreign and endogenous antigens1–4. Several lines of evidence indicate that ...