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  1. No Access

    Article

    The chromatin remodeller ACF acts as a dimeric motor to space nucleosomes

    Evenly spaced nucleosomes directly correlate with condensed chromatin and gene silencing. The ATP-dependent chromatin assembly factor (ACF) forms such structures in vitro and is required for silencing in vivo. AC...

    Lisa R. Racki, Janet G. Yang, Nariman Naber, Peretz D. Partensky, Ashley Acevedo… in Nature (2009)

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    Article

    Dynamics of nucleosome remodelling by individual ACF complexes

    The ATP-dependent chromatin assembly and remodelling factor (ACF) functions to generate regularly spaced nucleosomes, which are required for heritable gene silencing. The mechanism by which ACF mobilizes nucle...

    Timothy R. Blosser, Janet G. Yang, Michael D. Stone, Geeta J. Narlikar… in Nature (2009)

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    Article

    The chromatin-remodeling enzyme ACF is an ATP-dependent DNA length sensor that regulates nucleosome spacing

    Arrays of regularly spaced nucleosomes directly correlate with closed chromatin structures at silenced loci. The ATP-dependent chromatin-assembly factor (ACF) generates such arrays in vitro and is required for tr...

    Janet G Yang, Tina Shahian Madrid… in Nature Structural & Molecular Biology (2006)