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    Chapter

    Myelodysplasia-Related AML

    The myelodysplastic syndromes (MDSs) comprise a heterogeneous group of clonal stem cell disorders characterized by ineffective hematopoiesis (1). Because progression to acute myeloid leukemia (AML) occurs in one-...

    Jane E. Parker in Acute Myelogenous Leukemia (2007)

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    Article

    The Role of Apoptosis in the Pathogenesis of the Myelodysplastic Syndromes

    The paradoxical occurrence of peripheral cytopenias despite a normo/hypercellular marrow in myelodysplastic syndromes (MDS) has been attributed to excessive intramedullary hematopoietic cell apoptosis. It has ...

    Jane E. Parker, Ghulam J. Mufti in International Journal of Hematology (2001)