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Article
Combination anti-HIV antibodies provide sustained virological suppression
Antiretroviral therapy is highly effective in suppressing human immunodeficiency virus (HIV)1. However, eradication of the virus in individuals with HIV has not been possible to date2. Given that HIV suppression ...
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Article
Cerebral venous sinus thrombosis in infant with COVID-19
We present a rare case of cerebral venous sinus thrombosis in a COVID-19-positive, 2-month-old infant, to this day the youngest described patient with this rare combination of findings. He was hospitalized wit...
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Article
Distinct mechanisms of long-term virologic control in two HIV-infected individuals after treatment interruption of anti-retroviral therapy
Certain infected individuals suppress human immunodeficiency virus (HIV) in the absence of anti-retroviral therapy (ART). Elucidating the underlying mechanism(s) is of high interest. Here we present two contra...
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Article
Open AccessMacrophage-derived HIV-1 carries bioactive TGF-beta
Infected T cells and macrophages are the main producers of HIV-1 in infected individuals. Upon release from infected cells, HIV-1 incorporates various cellular membrane proteins, some of which are specific for...
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Article
Open AccessDevelopment of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals
Human immunodeficiency virus type 1 (HIV-1) latency represents the major barrier to virus eradication in infected individuals because cells harboring latent HIV-1 provirus are not affected by current antiretro...
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Article
Open AccessDNA cytosine methylation in the Bovine Leukemia Virus promoter is associated with latency in a Lymphoma-derived B-cell line : potential involvement of direct inhibition of CREB/CREM/ATF binding
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Article
Open AccessCpG methylation controls reactivation of HIV from latency
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Article
Open AccessThe epigenetic control of HERV loci encoding for fusogenic envelope glycoproteins in trophoblast
