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  1. No Access

    Article

    Implications of therapy choice on overall survival in metastatic renal cell carcinoma

    Purpose: To compare the effect of high-dose interleukin-2 (HD IL-2) vs other cytokine therapies on 1-, 2, and 5-yr overall survival in patients with metastatic renal cell cancer (RCC).

    Simrit Parmar, Alfred W. Rademaker, Bing B. Fung, James M. Kozlowski… in Medical Oncology (2005)

  2. No Access

    Chapter

    Transforming Growth Factor α: A Potential Autocrine Growth Regulator in Prostatic Carcinoma

    Since the classical observation of Huggins and Hodges in 1941 [1], the efficacy of androgen-ablative therapy has been well established in the management of patients with advanced prostate cancer. However, this...

    Chung Lee, Darlys R. Hofer… in Molecular and Cellular Biology of Prostate… (1991)

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    Chapter

    Role of Androgens and Extracellular Matrix in the Growth and Differentiation of Benign and Malignant Prostate Epithelial Cells

    Normal tissues maintain a balance between growth and differentiation. During normal adult life, the prostatic epithelium undergoes little net growth but synthesizes and secretes proteins such as prostate speci...

    Edward R. Sherwood, Chau-Jye Fong… in Molecular and Cellular Biology of Prostate… (1991)

  4. No Access

    Chapter

    The Impact of Androgen, Extracellular Matrix, and Stroma Upon Proliferation and Differentiation of Benign and Malignant Prostate Epithelial Cells

    Mesenchymal-epithelial interactions are thought to playa strategic role in androgen-induced regulation of prostate epithelial cell growth and differentiation. A more thorough understanding of this process has ...

    James M. Kozlowski, Edward R. Sherwood… in Molecular and Cellular Biology of Prostate… (1991)