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Article
Implications of therapy choice on overall survival in metastatic renal cell carcinoma
Purpose: To compare the effect of high-dose interleukin-2 (HD IL-2) vs other cytokine therapies on 1-, 2, and 5-yr overall survival in patients with metastatic renal cell cancer (RCC).
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Chapter
Cancer of the Bladder
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Chapter
Prostate Cancer
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Article
Acute adrenal insufficiency following unilateral radical nephrectomy: A case report
Adrenal insufficiency following unilateral radical nephrectomy has not been previously described in medical literature. We present a 78-year-old male patient who experienced a difficult postoperative course wi...
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Article
In vivo andin vitro approaches to study metastasis in human prostatic cancer
Prostate cancer is the most common malignancy in American males and is second only to lung cancer as a cause of death in the United States. Clinically, radical prostatectomy offers a patient with locally conta...
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Chapter
Transforming Growth Factor α: A Potential Autocrine Growth Regulator in Prostatic Carcinoma
Since the classical observation of Huggins and Hodges in 1941 [1], the efficacy of androgen-ablative therapy has been well established in the management of patients with advanced prostate cancer. However, this...
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Chapter
Role of Androgens and Extracellular Matrix in the Growth and Differentiation of Benign and Malignant Prostate Epithelial Cells
Normal tissues maintain a balance between growth and differentiation. During normal adult life, the prostatic epithelium undergoes little net growth but synthesizes and secretes proteins such as prostate speci...
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Chapter
The Impact of Androgen, Extracellular Matrix, and Stroma Upon Proliferation and Differentiation of Benign and Malignant Prostate Epithelial Cells
Mesenchymal-epithelial interactions are thought to playa strategic role in androgen-induced regulation of prostate epithelial cell growth and differentiation. A more thorough understanding of this process has ...