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    Small molecule antagonists of the TGF-β1/TGF-β receptor binding interaction

    Excessive and inappropriate action of transforming growth factor (TGF)-β has been implicated in the pathogenesis of several disease processes, especially cancer and fibrosis. To identify antagonists of the TGF...

    James K. Burmester, Sherry A. Salzman, Kai Qi Zhang, Richard A. Dart in Medical Oncology (2006)

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    Transforming growth factor-β and multidrug resistance in chronic lymphocytic leukemia

    Patients with chronic lymphocytic leukemia (CLL) frequently respond to initial treatment, but then become resistant to chemotherapy. Studies have shown one important cause of chemotherapeutic resistance to be ...

    William R Friedenberg, Sherry A Salzman, Sonja M Phan in Medical Oncology (1999)