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  1. Article

    Combined histomorphometric and gene-expression profiling applied to toxicology

    We have developed a unique methodology for the combined analysis of histomorphometric and gene-expression profiles amenable to intensive data mining and multisample comparison for a comprehensive approach to t...

    Andres Kriete, Mary K Anderson, Brad Love, John Freund, James J Caffrey in Genome Biology (2003)

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    Chapter

    Biochemical and Molecular Biological Characterization of Biotinylated Proteins of Plants

    At least six biotinylated polypeptides can be detected in extracts from plants (1). These polypeptides are approximately 240 kDa, 120 kDa, 75 kDa, 60 kDa, 39 kDa and 34 kDa in size. Furthermore, the biotin enz...

    James J. Caffrey, Yang Chen, Tomás Diez, Xueni Guan in Plant Lipid Metabolism (1995)

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    Chapter

    Biochemical and Molecular Biological Characterization of Acetyl-CoA Carboxylases

    Acetyl-CoA carboxylase (ACCase) catalyzes the ATP-dependent carboxylation of acetyl-CoA to form malonyl-CoA. Classically this reaction is considered to be the first, rate-limiting reaction of de novo fatty acid b...

    Basil J. Nikolau, James J. Caffrey, Tomás Diez, Ji-ying Huang in Plant Lipid Metabolism (1995)