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Article
Open AccessAn intersectional approach to identifying factors associated with anxiety and depression following the COVID-19 pandemic
The COVID-19 pandemic is impacting mental health, with some populations bearing a greater burden. In this cross-sectional online study, we examined the personal and intersectional factors associated with incre...
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Chapter
Prisoner Experiences of Prison Health in Scotland
Aim: This study investigated the prison and post-prison-related healthcare experiences of male prisoners in order to better inform future policy.
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Article
Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development
Transcriptional regulation plays a central role in controlling neural stem and progenitor cell proliferation and differentiation during neurogenesis. For instance, transcription factors from the nuclear factor...
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Article
A simple, web-based repository for the management, access and analysis of micrographic images
Microscopy is advancing at a rapid pace, enabling high-speed, high-resolution analyses to be conducted in a wide range of cellular contexts. For example, the capacity to quickly capture high-resolution images ...
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Article
Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development
Cerebellar granule neurons are the most numerous neuronal subtype in the central nervous system. Within the develo** cerebellum, these neurons are derived from a population of progenitor cells found within t...
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Article
Open AccessStandard setting in Australian medical schools
Standard setting of assessment is critical in quality assurance of medical programs. The aims of this study were to identify and compare the impact of methods used to establish the passing standard by the 13 m...
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Article
Cell-type-specific expression of NFIX in the develo** and adult cerebellum
Transcription factors from the nuclear factor one (NFI) family have been shown to play a central role in regulating neural progenitor cell differentiation within the embryonic and post-natal brain. NFIA and NF...
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Article
Complex multi-enhancer contacts captured by genome architecture map**
The organization of the genome in the nucleus and the interactions of genes with their regulatory elements are key features of transcriptional control and their disruption can cause disease. Here we report a g...
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Chapter
Operational ACCESS-TC: Vortex Specification, 4DVAR Initialization, Verification and Structure Diagnostics
The Australian Community Climate and Earth System Simulator, ACCESS (Puri et al., 2010, 2012) has been configured for operational and research applications on Tropical Cyclones. ACCESS is an implementation at ...
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Chapter
Map** and Visualizing Spatial Genome Organization
Non-random genome organization and its correlation with various nuclear activities point to the existence of functional chromatin folding and positioning patterns. The importance of genome architecture is high...
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Article
Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture
Human population genomic studies, including whole‐genome sequencing, were undertaken to identify determinants of bone mineral density (BMD), a major predictor of osteoporotic fractures. Non‐coding variants wit...
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Chapter and Conference Paper
An Experimental Approach to Identifying Prominent Factors in Video Game Difficulty
This paper explores a full factorial analysis methodology to identify game factors with practical significance on the level of difficulty of a game. To evaluate this methodology, we designed an experimental te...
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Article
Open AccessThree-dimensional modeling of chromatin structure from interaction frequency data using Markov chain Monte Carlo sampling
Long-range interactions between regulatory DNA elements such as enhancers, insulators and promoters play an important role in regulating transcription. As chromatin contacts have been found throughout the huma...
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Article
Increasing prevalence of domiciliary ventilation: changes in service demand and provision in the South West of the UK
We examine the incidence and prevalence of domiciliary ventilation in the South West region of the UK, assess trends over 15 years, and describe patient outcome. We conducted a retrospective review of all pati...
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Article
Accidental ingestion of dosulepin presenting as atrial flutter in a child
This case highlights the importance of considering drug ingestion when the clinical features at presentation are unusual. To our knowledge, this is the first report of atrial flutter secondary to tricyclic ant...
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Protocol
Computing Chromosome Conformation
The “Chromosome Conformation Capture” (3C) and 3C-related technologies are used to measure physical contacts between DNA segments at high resolution in vivo. 3C studies indicate that genomes are likely organiz...
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Article
Open AccessChromatin conformation signatures of cellular differentiation
One of the major genomics challenges is to better understand how correct gene expression is orchestrated. Recent studies have shown how spatial chromatin organization is critical in the regulation of gene expr...
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Article
Gender Differences in Sado-Masochistic Arousal Among College Students
This paper tests three competing explanationsfor male-female differences in sado-masochistic sexualarousal. The male arousal hypothesis posits that becauseof socialization that emphasizes sexual aggression and...
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Article
Taste aversion and passive avoidance in rats with hippocampal lesions
Rats with near total hippocampal lesions were compared with cortical and normal control animals on taste aversion and passive avoidance conditioning. While the initial magnitude of the taste aversion induced t...
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Article
Repeated Freeze–Thaw Cycles in Cryosurgery
FREEZING temperatures have been in use in surgery for many years as a means of local tissue destruction. Recent experimental investigation has shown that such freezing will give a reproducible area of cell dea...
