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Article
Open AccessAdvancing peristalsis deciphering in mouse small intestine by multi-parameter tracking
Assessing gastrointestinal motility lacks simultaneous evaluation of intraluminal pressure (ILP), circular muscle (CM) and longitudinal muscle (LM) contraction, and lumen emptying. In this study, a sophisticat...
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Article
The biology of mammalian multi-copper ferroxidases
The mammalian multicopper ferroxidases (MCFs) ceruloplasmin (CP), hephaestin (HEPH) and zyklopen (ZP) comprise a family of conserved enzymes that are essential for body iron homeostasis. Each of these enzymes ...
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Article
Open AccessA direct comparison of divalent metal-ion transporter (DMT1) and hinokitiol, a potential small molecule replacement
Hinokitiol, a natural lipophilic chelator, appears capable of replacing several iron transporters after they have been genetically ablated. Divalent metal-ion transporter (DMT1) is the major iron importer in e...
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Chapter
A History of Soil Research with Emphasis on Pedology
While commentary on the productivity of Irish pastures can be dated as far back as 55 BC, direct references to the different kinds of soil only begin in the eighth century AD. Early scientific information on I...
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Article
Open AccessPopulation genetics of cobia (Rachycentron canadum) in the Gulf of Thailand and Andaman Sea: fisheries management implications
Population genetics has been recognized as a key component of policy development for fisheries and conservation management and aquaculture development. This study aims to evaluate the genetic diversity and pop...
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Article
Immunoreactive Hephaestin and ferroxidase activity are present in the cytosolic fraction of rat enterocytes
Discovered over a decade ago, hephaestin (Heph) has been implicated as a ferroxidase (FOX) vital for intestinal iron absorption. Stringent structural or kinetic data derived from purified, native protein is ho...
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Article
Open AccessPrediction of synergistic transcription factors by function conservation
Previous methods employed for the identification of synergistic transcription factors (TFs) are based on either TF enrichment from co-regulated genes or phylogenetic footprinting. Despite the success of these ...
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Article
Open AccessPromoter analysis of intestinal genes induced during iron-deprivation reveals enrichment of conserved SP1-like binding sites
Iron-deficiency leads to the induction of genes related to intestinal iron absorption and homeostasis. By analyzing a large GeneChip® dataset from the rat intestine, we identified a large cluster of 228 genes tha...
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Article
The SLC20 family of proteins: dual functions as sodium-phosphate cotransporters and viral receptors
The SLC20 family transport proteins were originally identified as retroviral receptors (called Glvr-1 and Ram-1). Since then, they have been shown to function as sodium-phosphate (Na/Pi) cotransporters, and have ...
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Article
Genetic Screening for X-Linked Hypophosphatemic Mice and Ontogenic Characterization of the Defect in the Renal Sodium-Phosphate Transporter
X-linked hypophosphatemic (Hyp) rickets is characterized by short stature, rickets, and bone abnormalities. Biochemically, hypophosphatemia and decreased renal reabsorption of phosphate are the hallmark of the...
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Article
Acute effects of oleic acid-induced lung injury in baboons
Oleic acid induces lung injury in the baboon. Within 90 min of intravenous oleic acid injection, there are significant increases relative to baseline in the bronchoalveolar lavage fluid (BALF) contents of tota...
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Article
Independence of sensitivity on different foveal areas
Evidence suggests that for close retinal areas a correlation in sensitivity exists between the areas. Correlations as a function of distance from fixation and between areas were studied. In Experiment I, both ...
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Article
The perception of multiple simultaneously presented forms as a function of foveal spacing
Using five capital letters as the form stimuli and tachistoscopic presentation, an exposure duration was determined for each S that yielded 80% identification accuracy when single letter displays were presente...
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Article
Investigation of the effect of a priming stimulus on backward masking
Using the backward masking paradigm of a form followed shortly after exposure by a ring, the effect of a priming stimulus appearing 100, 50, and 10 ms. prior to the form was investigated. Although the backward...
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Article
Backward masking in vision
Recognition accuracy for capital letters, A, T, and U was assessed when the exposure of a letter was either accompanied or followed at delays of 0 to 250 ms. by exposure of a ring stimulus that circumscribed t...
