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Article
Butyrate induces development-dependent necrotizing enterocolitis-like intestinal epithelial injury via necroptosis
The accumulation of short-chain fatty acids (SCFAs) from bacterial fermentation may adversely affect the under-developed gut as observed in premature newborns at risk for necrotizing enterocolitis (NEC). This ...
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Article
Open AccessAn Adaptable and Scalable Generator of Distributed Massive MIMO Baseband Processing Systems
This paper presents an algorithm-adaptable, scalable, and platform-portable generator for massive multiple-input multiple-output (MIMO) baseband processing systems. This generator is written in Chisel hardware...
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Article
Open AccessA multicenter evaluation of viral bloodstream detections in children presenting to the Emergency Department with suspected systemic infection
Fever is a common symptom in children presenting to the Emergency Department (ED). We aimed to describe the epidemiology of systemic viral infections and their predictive values for excluding serious bacterial...
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Chapter
System Integration of RISC-V Processors with FD-SOI
Improving the energy efficiency of processor systems-on-chip (SoCs) is key to improving their performance and utility. The FD-SOI silicon process enables integrated systems that can deliver dramatic improvemen...
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Article
Open AccessEvolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa
Pseudomonas aeruginosa colonises the upper airway of cystic fibrosis (CF) patients, providing a reservoir of host-adapted genotypes that subsequently establish chronic lung infection. We previously experimentally...
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Article
Race and Prevalence of Large Bowel Polyps Among the Low-Income and Uninsured in South Carolina
Compared to whites, blacks have higher colorectal cancer incidence and mortality rates and are at greater risk for early-onset disease. The reasons for this racial disparity are poorly understood, but one cont...
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Article
Open AccessHousing Characteristics and their Influence on Health-Related Quality of Life in Persons Living with HIV in Ontario, Canada: Results from the Positive Spaces, Healthy Places Study
Although lack of housing is linked with adverse health outcomes, little is known about the impacts of the qualitative aspects of housing on health. This study examined the association between structural elemen...
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Article
Atomic inner-shell X-ray laser at 1.46 nanometres pumped by an X-ray free-electron laser
A femtosecond, high-intensity atomic X-ray laser with a photon energy of 849 electronvolts is produced in singly ionized neon by pum** using an X-ray free-electron laser.
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Article
“Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario
Positive Spaces, Healthy Places (PSHP) is the first longitudinal community-based research (CBR) initiative in Canada to examine housing stability and its relationship to health related quality of life (HRQOL) ...
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Article
Open AccessStandardized observation of neighbourhood disorder: does it work in Canada?
There is a growing body of evidence that where you live is important to your health. Despite numerous previous studies investigating the relationship between neighbourhood deprivation (and structure) and resid...
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Article
Open AccessPaternal psychosocial work conditions and mental health outcomes: A case-control study
The role of social and family environments in the development of mental health problems among children and youth has been widely investigated. However, the degree to which parental working conditions may impac...
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East Timor in the Arc of Instability
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Article
Income segregation, income inequality and mortality in North American metropolitan areas
There is a large sociological literature on racial- class-, and economically- based segregation in the United States and there is some evidence that residential segregation by income may have deleterious healt...
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Article
Identification of Hereditary Hemorrhagic Telangiectasia Type 1 in Newborns by Protein Expression and Mutation Analysis of Endoglin
Hereditary hemorrhagic telangiectasia (HHT) is a dominantly inherited vascular disorder that is heterogeneous in terms of age of onset and clinical manifestations. Endoglin is the gene mutated in HHT1, which is a...
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Chapter
Defective Glycosyltransferases are Not Good for Your Health
The history of biochemical research on the structure and function of glycoproteins and glycolipids (glycoconjugates) dates back to the early 19th century (Montreuil, 1995). The variety of these macromolecules,...
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Article
Association of gap junctions with endoplasmic reticulum in rat parotid glands
Examination of the parotid gland of the rat has shown specific associations of cisterns of the endoplasmic reticulum with gap junctions. About 20% of the junctions are so intimately associated with cisterns of...