5 Result(s)
within
Jaime A. Castro-Mondragon
-
Article
Open AccessEpromoters function as a hub to recruit key transcription factors required for the inflammatory response
Gene expression is controlled by the involvement of gene-proximal (promoters) and distal (enhancers) regulatory elements. Our previous results demonstrated that a subset of gene promoters, termed Epromoters, w...
-
Article
Open AccessCrosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Abnormal DNA methylation is observed as an early event in breast carcinogenesis. However, how such alterations arise is still poorly understood. microRNAs (miRNAs) regulate gene expression at the post-transcri...
-
Article
Genome-wide characterization of mammalian promoters with distal enhancer functions
Salvatore Spicuglia and colleagues use a high-throughput reporter assay to identify a set of mammalian promoters, termed Epromoters, that display enhancer activity and have distinct genomic and epigenomic feat...
-
Protocol
RSAT::Plants: Motif Discovery in ChIP-Seq Peaks of Plant Genomes
In this protocol, we explain how to run ab initio motif discovery in order to gather putative transcription factor binding motifs (TFBMs) from sets of genomic regions returned by ChIP-seq experiments. The protoco...
-
Protocol
RSAT::Plants: Motif Discovery Within Clusters of Upstream Sequences in Plant Genomes
The plant-dedicated mirror of the Regulatory Sequence Analysis Tools (RSAT, http://plants.rsat.eu) offers specialized options for researchers dealing with plant tr...
