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133 Result(s)
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Article
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention
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Article
Lipoprotein(a), platelet function and cardiovascular disease
Lipoprotein(a) (Lp(a)) is associated with atherothrombosis through several mechanisms, including putative antifibrinolytic properties. However, genetic association studies have not demonstrated an association ...
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Coronary computed tomography angiographic detection of in-stent restenosis via deep learning reconstruction: a feasibility study
Evaluation of in-stent restenosis (ISR), especially for small stents, remains challenging during computed tomography (CT) angiography. We used deep learning reconstruction to quantify stent strut thickness and...
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Article
Progression of non-obstructive coronary plaque: a practical CCTA-based risk score from the PARADIGM registry
No clear recommendations are endorsed by the different scientific societies on the clinical use of repeat coronary computed tomography angiography (CCTA) in patients with non-obstructive coronary artery diseas...
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Article
Open AccessCCTA-based CABG SYNTAX Score: a tool to evaluate completeness of coronary segment revascularization after bypass surgery
To describe the updated coronary computed tomographic angiography (CCTA)-based coronary artery bypass graft (CABG) anatomic SYNTAX Score (aSS) and assess its utility and reproducibility for assessing the compl...
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Article
Accelerated reduction in global cardiovascular disease is essential to achieve the Sustainable Development Goals
Cardiovascular health is essential to achieving the United Nations Sustainable Development Goals (SDGs), particularly SDG3.4. Barriers include inequalities and a lack of political will and prioritization. A co...
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Article
Open AccessTreatment recommendation based on SYNTAX score 2020 derived from coronary computed tomography angiography and invasive coronary angiography
The diagnostic performance of the SYNTAX score 2020 (SS-2020) when calculated using CCTA remains unknown. This study aimed to compare treatment recommendations based on the SS-2020 derived from coronary comput...
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Article
Open AccessA foundational vision transformer improves diagnostic performance for electrocardiograms
The electrocardiogram (ECG) is a ubiquitous diagnostic modality. Convolutional neural networks (CNNs) applied towards ECG analysis require large sample sizes, and transfer learning approaches for biomedical pr...
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Article
Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis
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Article
The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis
Calcific aortic valve disease (CAVD) and stenosis have a complex pathogenesis, and no therapies are available that can halt or slow their progression. Several studies have shown the presence of apolipoprotein-...
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Article
Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research
Understanding the natural history of coronary artery atherosclerosis is necessary to determine prognosis and prescribe effective therapies. Traditional management of coronary artery disease has focused on the ...
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Article
Open AccessMulti-center retrospective cohort study applying deep learning to electrocardiograms to identify left heart valvular dysfunction
Aortic Stenosis and Mitral Regurgitation are common valvular conditions representing a hidden burden of disease within the population. The aim of this study was to develop and validate deep learning-based scre...
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Article
Open AccessGlycemic control is independently associated with rapid progression of coronary atherosclerosis in the absence of a baseline coronary plaque burden: a retrospective case–control study from the PARADIGM registry
The baseline coronary plaque burden is the most important factor for rapid plaque progression (RPP) in the coronary artery. However, data on the independent predictors of RPP in the absence of a baseline coron...
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Article
Optical coherence tomography in coronary atherosclerosis assessment and intervention
Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the opti...
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Article
Coronary plaque vulnerability in statin-treated patients with elevated LDL-C and hs-CRP: optical coherence tomography study
There have been no previous attempts to assess coronary plaque morphology in statin-treated patients with combined residual cholesterol and inflammatory risk. The aim of this study was to characterize the morp...
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Article
Relationship between hemoglobin A1C and characteristics of plaque vulnerability in stable coronary disease: an optical coherence tomography study
Patients with diabetes mellitus are at increased risk of cardiovascular events. We aimed to analyze the impact of serum HbA1c levels on coronary plaque characteristics in stable coronary disease. Two hundred s...
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Open AccessDifferential progression of coronary atherosclerosis according to plaque composition: a cluster analysis of PARADIGM registry data
Patient-specific phenoty** of coronary atherosclerosis would facilitate personalized risk assessment and preventive treatment. We explored whether unsupervised cluster analysis can categorize patients with c...
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Open AccessSaphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery
Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored ...
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Book
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Chapter
Clinical Molecular Imaging of Inflammation and Calcification in Atherosclerosis
Atherosclerotic cardiovascular disease is the leading cause of mortality worldwide [1]. Once considered relatively inert gruel deposition on the vessel wall, atherosclerosis is now recognized as a highly dynam...