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  1. Article

    Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention

    Makoto Araki, Seung-Jung Park, Harold L. Dauerman in Nature Reviews Cardiology (2024)

  2. No Access

    Article

    Lipoprotein(a), platelet function and cardiovascular disease

    Lipoprotein(a) (Lp(a)) is associated with atherothrombosis through several mechanisms, including putative antifibrinolytic properties. However, genetic association studies have not demonstrated an association ...

    Harpreet S. Bhatia, Richard C. Becker, Gregor Leibundgut in Nature Reviews Cardiology (2024)

  3. No Access

    Article

    Coronary computed tomography angiographic detection of in-stent restenosis via deep learning reconstruction: a feasibility study

    Evaluation of in-stent restenosis (ISR), especially for small stents, remains challenging during computed tomography (CT) angiography. We used deep learning reconstruction to quantify stent strut thickness and...

    Hideki Kawai, Sadako Motoyama, Masayoshi Sarai, Yoshihiro Sato in European Radiology (2024)

  4. No Access

    Article

    Progression of non-obstructive coronary plaque: a practical CCTA-based risk score from the PARADIGM registry

    No clear recommendations are endorsed by the different scientific societies on the clinical use of repeat coronary computed tomography angiography (CCTA) in patients with non-obstructive coronary artery diseas...

    Gianluca Pontone, Alexia Rossi, Andrea Baggiano, Daniele Andreini in European Radiology (2024)

  5. Article

    Open Access

    CCTA-based CABG SYNTAX Score: a tool to evaluate completeness of coronary segment revascularization after bypass surgery

    To describe the updated coronary computed tomographic angiography (CCTA)-based coronary artery bypass graft (CABG) anatomic SYNTAX Score (aSS) and assess its utility and reproducibility for assessing the compl...

    Nozomi Kotoku, Patrick W. Serruys in The International Journal of Cardiovascula… (2023)

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    Article

    Accelerated reduction in global cardiovascular disease is essential to achieve the Sustainable Development Goals

    Cardiovascular health is essential to achieving the United Nations Sustainable Development Goals (SDGs), particularly SDG3.4. Barriers include inequalities and a lack of political will and prioritization. A co...

    Daniel J. Piñeiro, Elisa Codato, Jeremiah Mwangi in Nature Reviews Cardiology (2023)

  7. Article

    Open Access

    Treatment recommendation based on SYNTAX score 2020 derived from coronary computed tomography angiography and invasive coronary angiography

    The diagnostic performance of the SYNTAX score 2020 (SS-2020) when calculated using CCTA remains unknown. This study aimed to compare treatment recommendations based on the SS-2020 derived from coronary comput...

    Shinichiro Masuda, Patrick W. Serruys in The International Journal of Cardiovascula… (2023)

  8. Article

    Open Access

    A foundational vision transformer improves diagnostic performance for electrocardiograms

    The electrocardiogram (ECG) is a ubiquitous diagnostic modality. Convolutional neural networks (CNNs) applied towards ECG analysis require large sample sizes, and transfer learning approaches for biomedical pr...

    Akhil Vaid, Joy Jiang, Ashwin Sawant, Stamatios Lerakis in npj Digital Medicine (2023)

  9. Article

    Author Correction: The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis

    Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini in Nature Reviews Cardiology (2023)

  10. No Access

    Article

    The contribution of amyloid deposition in the aortic valve to calcification and aortic stenosis

    Calcific aortic valve disease (CAVD) and stenosis have a complex pathogenesis, and no therapies are available that can halt or slow their progression. Several studies have shown the presence of apolipoprotein-...

    Karan Sud, Navneet Narula, Elena Aikawa, Eloisa Arbustini in Nature Reviews Cardiology (2023)

  11. No Access

    Article

    Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research

    Understanding the natural history of coronary artery atherosclerosis is necessary to determine prognosis and prescribe effective therapies. Traditional management of coronary artery disease has focused on the ...

    Prakriti Gaba, Bernard J. Gersh, James Muller, Jagat Narula in Nature Reviews Cardiology (2023)

  12. Article

    Open Access

    Multi-center retrospective cohort study applying deep learning to electrocardiograms to identify left heart valvular dysfunction

    Aortic Stenosis and Mitral Regurgitation are common valvular conditions representing a hidden burden of disease within the population. The aim of this study was to develop and validate deep learning-based scre...

    Akhil Vaid, Edgar Argulian, Stamatios Lerakis in Communications Medicine (2023)

  13. Article

    Open Access

    Glycemic control is independently associated with rapid progression of coronary atherosclerosis in the absence of a baseline coronary plaque burden: a retrospective case–control study from the PARADIGM registry

    The baseline coronary plaque burden is the most important factor for rapid plaque progression (RPP) in the coronary artery. However, data on the independent predictors of RPP in the absence of a baseline coron...

    Ki-Bum Won, Byoung Kwon Lee, Fay Y. Lin, Martin Hadamitzky in Cardiovascular Diabetology (2022)

  14. No Access

    Article

    Optical coherence tomography in coronary atherosclerosis assessment and intervention

    Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the opti...

    Makoto Araki, Seung-Jung Park, Harold L. Dauerman in Nature Reviews Cardiology (2022)

  15. No Access

    Article

    Coronary plaque vulnerability in statin-treated patients with elevated LDL-C and hs-CRP: optical coherence tomography study

    There have been no previous attempts to assess coronary plaque morphology in statin-treated patients with combined residual cholesterol and inflammatory risk. The aim of this study was to characterize the morp...

    Surbhi Chamaria, Hiroki Ueyama in The International Journal of Cardiovascula… (2022)

  16. No Access

    Article

    Relationship between hemoglobin A1C and characteristics of plaque vulnerability in stable coronary disease: an optical coherence tomography study

    Patients with diabetes mellitus are at increased risk of cardiovascular events. We aimed to analyze the impact of serum HbA1c levels on coronary plaque characteristics in stable coronary disease. Two hundred s...

    Hiroki Ueyama, Keisuke Yasumura in The International Journal of Cardiovascula… (2022)

  17. Article

    Open Access

    Differential progression of coronary atherosclerosis according to plaque composition: a cluster analysis of PARADIGM registry data

    Patient-specific phenoty** of coronary atherosclerosis would facilitate personalized risk assessment and preventive treatment. We explored whether unsupervised cluster analysis can categorize patients with c...

    Yeonyee E. Yoon, Lohendran Baskaran, Benjamin C. Lee in Scientific Reports (2021)

  18. Article

    Open Access

    Saphenous vein valve assessment utilizing upright CT to potentially improve graft assessment for bypass surgery

    Saphenous veins (SVs) are frequently employed as bypass grafts. The SV graft failure is predominantly seen at the valve site. Avoiding valves during vein harvest would help reduce graft failure. We endeavored ...

    Takehiro Nakahara, Minoru Yamada, Yoichi Yokoyama, Yoshitake Yamada in Scientific Reports (2021)

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    Book

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    Chapter

    Clinical Molecular Imaging of Inflammation and Calcification in Atherosclerosis

    Atherosclerotic cardiovascular disease is the leading cause of mortality worldwide [1]. Once considered relatively inert gruel deposition on the vessel wall, atherosclerosis is now recognized as a highly dynam...

    Azar Radfar, Jack P. Andrews, Marc R. Dweck, Jagat Narula in Atlas of Nuclear Cardiology (2021)

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