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  1. Article

    Open Access

    Correction: 7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells

    Won Seok Ju, Sang Young Seo, Seong-eun Mun, Kyongtae Kim, ** Ok Yu in Discover Oncology (2023)

  2. Article

    Open Access

    7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells

    Malignant melanoma is a skin cancer with poor prognosis and high resistance to conventional treatment. 7,8-dihydroxyflavone (7,8-DHF) has shown anti-carcinogenic, anti-inflammatory, anti-oxidant, and pharmacol...

    Won Seok Ju, Sang Young Seo, Seong-eun Mun, Kyongtae Kim, ** Ok Yu in Discover Oncology (2023)

  3. Article

    Open Access

    Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model

    Non-alcoholic fatty liver disease (NAFLD) begins as simple hepatic steatosis, but further progress to chronic liver diseases results in severe liver damage and hepatic failure. However, therapeutic options are...

    Jae-Sung Ryu, Minji Lee, Seon Ju Mun, Sin-Hyoung Hong in Journal of Biological Engineering (2019)

  4. Article

    Open Access

    A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming

    Targeting hair follicle regeneration has been investigated for the treatment of hair loss, and fundamental studies investigating stem cells and their niche have been described. However, knowledge of stem cell ...

    Myung ** Son, Jae Kap Jeong, Youjeong Kwon in Experimental & Molecular Medicine (2018)

  5. Article

    Open Access

    Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells

    Emerging evidence has emphasized the importance of cancer therapies targeting an abnormal metabolic state of tumor-initiating cells (TICs) in which they retain stem cell-like phenotypes and nicotinamide adenin...

    Myung ** Son, Jae-Sung Ryu, Jae Yun Kim in Experimental & Molecular Medicine (2017)

  6. No Access

    Article

    Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers

    An epithelial cell adhesion molecule (EpCAM) was selectively expressed in human colorectal carcinoma. Treatment with plant-derived anti-EpCAM mAb (mAbP CO17-1A) and RAW264.7 cells inhibited cell growth in the hum...

    Jae-Sung Ryu, Ju-Taek Lee, Malg-Um Lim, Mi-Ran Hwang in Biotechnology Letters (2013)

  7. Article

    Open Access

    Erratum: Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer

    Correction to: Experimental & Molecular Medicine (2011) 43, 693–701; doi:10.3858/emm.2011.43.12.080 The authors request to correct the project number PJ007492 (correct one) from PJ007187 (wrong number) on the ...

    Dong Hoon Kwak, Jae-Sung Ryu, Chang-Hyun Kim in Experimental & Molecular Medicine (2012)

  8. Article

    Open Access

    Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer

    The human colorectal carcinoma-associated GA733 antigen epithelial cell adhesion molecule (EpCAM) was initially described as a cell surface protein selectively expressed in some myeloid cancers. Gangliosides a...

    Dong Hoon Kwak, Jae-Sung Ryu, Chang-Hyun Kim in Experimental & Molecular Medicine (2011)

  9. No Access

    Article

    Comparison of ganglioside expression between human adipose- and dental pulp-derived stem cell differentiation into osteoblasts

    Human adipose-derived stem cells (hADSCs) and dental pulp-derived stem cells (hDPSCs) have been considered alternative sources of adult stem cells because of their potential to trans-differentiate into multipl...

    So Hyun Lee, Jae-Sung Ryu, Jeong-Woong Lee in Archives of Pharmacal Research (2010)

  10. No Access

    Article

    Expression of ganglioside GT1b in mouse embryos at different developmental stages after cryopreservation

    Gangliosides are a family of sialic acid-containing glycosphingolipids that are abundant in neurons and have a variety of functions in develo** and mature tissues. We examined the expression of ganglioside G...

    Bo-Hyun Kim, Ji-Ung Jung, Kisung Ko, Won-Sin Kim in Archives of Pharmacal Research (2008)