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Open AccessCorrection: 7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells
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Open Access7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells
Malignant melanoma is a skin cancer with poor prognosis and high resistance to conventional treatment. 7,8-dihydroxyflavone (7,8-DHF) has shown anti-carcinogenic, anti-inflammatory, anti-oxidant, and pharmacol...
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Article
Open AccessTargeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model
Non-alcoholic fatty liver disease (NAFLD) begins as simple hepatic steatosis, but further progress to chronic liver diseases results in severe liver damage and hepatic failure. However, therapeutic options are...
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Open AccessA novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming
Targeting hair follicle regeneration has been investigated for the treatment of hair loss, and fundamental studies investigating stem cells and their niche have been described. However, knowledge of stem cell ...
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Article
Open AccessUpregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells
Emerging evidence has emphasized the importance of cancer therapies targeting an abnormal metabolic state of tumor-initiating cells (TICs) in which they retain stem cell-like phenotypes and nicotinamide adenin...
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Article
Plant-derived mAbs have effective anti-cancer activities by increasing ganglioside expression in colon cancers
An epithelial cell adhesion molecule (EpCAM) was selectively expressed in human colorectal carcinoma. Treatment with plant-derived anti-EpCAM mAb (mAbP CO17-1A) and RAW264.7 cells inhibited cell growth in the hum...
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Open AccessErratum: Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer
Correction to: Experimental & Molecular Medicine (2011) 43, 693–701; doi:10.3858/emm.2011.43.12.080 The authors request to correct the project number PJ007492 (correct one) from PJ007187 (wrong number) on the ...
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Open AccessRelationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer
The human colorectal carcinoma-associated GA733 antigen epithelial cell adhesion molecule (EpCAM) was initially described as a cell surface protein selectively expressed in some myeloid cancers. Gangliosides a...
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Comparison of ganglioside expression between human adipose- and dental pulp-derived stem cell differentiation into osteoblasts
Human adipose-derived stem cells (hADSCs) and dental pulp-derived stem cells (hDPSCs) have been considered alternative sources of adult stem cells because of their potential to trans-differentiate into multipl...
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Expression of ganglioside GT1b in mouse embryos at different developmental stages after cryopreservation
Gangliosides are a family of sialic acid-containing glycosphingolipids that are abundant in neurons and have a variety of functions in develo** and mature tissues. We examined the expression of ganglioside G...