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Open AccessUnderstanding the molecular aspects of oriental obesity pattern differentiation using DNA microarray
Human constitution, the fundamental basis of oriental medicine, is categorized into different patterns for a particular disease according to the physical, physiological, and clinical characteristics of the ind...
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Article
A thermal simulation of the DDI development of a multi-channel package for high-definition LCD panels
A multi-channel display driver integrated circuit (DDI), which is the core part of a liquid crystal display (LCD) television (TV), was proposed. The introduction of multi-channel DDIs in LCD TVs results in the...
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Article
Gene expression profiling of Bangpungtongseong-san (Bofutsushosan) and Bangkihwangki-tang (Boiogito) administered individuals
Bangpungtongseong-san (Bofutsushosan, BTS) and Bangkihwangki-tang (Boiogito, BOT) are widely prescribed Korean, Japanese and Chinese traditional herbal medicines used to clinically prevent or improve obesity. ...
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Article
Selection and optimization of asymmetric siRNA targeting the human c-MET gene
The silencing of specific oncogenes via RNA interference (RNAi) holds great promise for the future of cancer therapy. RNAi is commonly carried out using small interfering RNA (siRNA) composed of a 19 bp duplex...
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Article
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
Geographic atrophy (GA), an untreatable advanced form of age-related macular degeneration, results from retinal pigmented epithelium (RPE) cell degeneration. Here we show that the microRNA (miRNA)-processing e...
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Evaluation of RNA amplification method for high-density DNA microarray
DNA microarray technique is currently one of the most widely used methods for genome scale expression analysis with numerous applications. For DNA microarray analysis of the gene expression of small number of ...
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Article
HIF-1α-dependent gene expression program during the nucleic acid-triggered antiviral innate immune responses
Recent studies suggest a novel role of HIF-1α under non-hypoxic conditions, including antibacterial and antiviral innate immune responses. However, the identity of the pathogen-associated molecular pattern whi...
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Article
Open AccessbZIPDB : A database of regulatory information for human bZIP transcription factors
Basic region-leucine zipper (bZIP) proteins are a class of transcription factors (TFs) that play diverse roles in eukaryotes. Malfunctions in these proteins lead to cancer and various other diseases. For detai...